Centro de Química Estrutural, Instituto Superior Técnico, Universidade de Lisboa, Av. Rovisco Pais, 1049- 001 Lisboa, Portugal.
Curr Med Chem. 2019;26(35):6412-6437. doi: 10.2174/0929867326666190124124350.
The search for new metal-efficient drugs has attracted considerable attention of the scientific community. Among them, ruthenium complexes have emerged as an excellent alternative of platinum complexes. This review presents a thorough and timely coverage of the synthesis, biological activity and medicinal applications of ruthenium complexes bearing carbohydrate ligands, allowing a large community of readers, in particularly the community that works in organic, inorganic, bioorganometallic and medicinal chemistry, ready access to the most relevant examples.
寻找新的金属效率药物引起了科学界的极大关注。其中，钌配合物已成为铂配合物的极佳替代品。 本文综述了具有碳水化合物配体的钌配合物的合成、生物活性和药用应用，为广大读者，特别是从事有机、无机、生物有机金属和药物化学的读者提供了最相关的实例。
