Kongre Vaishali A, Pol Sae S, Bharadwaj Renu S, Gurav Yogesh K, Chadha Mandeep S, Tandale Babasaheb V, Deoshatwar Avinash R
Internal Medicine, B. J. Government Medical College & Sassoon General Hospitals, Pune, IND.
Epidemiology, National Institute of Virology, Pune, IND.
Cureus. 2018 Nov 16;10(11):e3601. doi: 10.7759/cureus.3601.
Influenza-like illness (ILI) and acute respiratory infection (ARI) are common presentations during winter, and indiscriminate antibiotic use contributes significantly to the emerging post-antibiotic era. Although viral agents causing ILI are predominant, they are indistinguishable from the bacterial agents based on the clinical features alone. The present study was aimed at determining the bacterial agents associated with ILI and their susceptibility pattern during a study done in a community setting in Pune during a surveillance of ILI between March 2013 to November 2016. Throat swabs from 512 suspected ILI cases were processed, and organisms were identified by the standard conventional method. An antimicrobial susceptibility testing was done as per the Clinical Laboratory Standard Institute (CLSI) guidelines. The patients comprised 238 males and 274 females with the majority (38.7%) in the age group of ≤10 years. Bacteria could be isolated from 9.8 % of the patients. The predominant bacteria included beta-hemolytic (42%) followed by group G (30%) and group A (20%). All organisms were sensitive to Penicillin except two isolates of (50%). Tetracycline (98.8%) and ciprofloxacin (87%) were the next most effective drugs. Overall resistance was observed for erythromycin (37%) and co-trimoxazole (32%).
流感样疾病（ILI）和急性呼吸道感染（ARI）是冬季常见的病症，抗生素的滥用在新兴的后抗生素时代中起到了重要作用。尽管引起ILI的病毒病原体占主导，但仅根据临床特征无法将它们与细菌病原体区分开来。本研究旨在确定2013年3月至2016年11月在浦那社区环境中进行的ILI监测期间与ILI相关的细菌病原体及其药敏模式。对512例疑似ILI病例的咽拭子进行处理，并通过标准常规方法鉴定病原体。根据临床实验室标准协会（CLSI）指南进行抗菌药物敏感性测试。患者包括238名男性和274名女性，大多数（38.7%）年龄在≤10岁组。9.8%的患者分离出细菌。主要细菌包括β溶血性（42%），其次是G组（30%）和A组（20%）。除两株（50%）分离菌外，所有病原体对青霉素敏感。四环素（98.8%）和环丙沙星（87%）是其次最有效的药物。观察到红霉素（37%）和复方新诺明（32%）总体耐药。
