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[Derivatives of phenoxyacetamide and antimycotic activity].

作者信息

Daidone G, Raffa D, Bajardi M L, Plescia S, Milici M

机构信息

Dipartimento di Chimica e Tecnologie Farmaceutiche, Universita di Palermo.

出版信息

Farmaco Sci. 1988 Sep;43(9):753-61.

PMID:3068075
Abstract

Novel N-(3-methyl-4-R-isoxazol-5-yl)-2-R1-4-R2-phenoxyacetamides and N-(3-methyl-4-R-isoxazol-5-yl)-2-(2-R1-4-R2-phenoxyacetamido) benzamides were prepared and tested against Candida albicans and Cryptococcus neoformans. The results of the antimicrobial assay showed that the presence of two amidic groups usually enhances antimycotic activity.

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