Daidone G, Raffa D, Bajardi M L, Plescia S, Milici M
Dipartimento di Chimica e Tecnologie Farmaceutiche, Universita di Palermo.
Farmaco Sci. 1988 Sep;43(9):753-61.
Novel N-(3-methyl-4-R-isoxazol-5-yl)-2-R1-4-R2-phenoxyacetamides and N-(3-methyl-4-R-isoxazol-5-yl)-2-(2-R1-4-R2-phenoxyacetamido) benzamides were prepared and tested against Candida albicans and Cryptococcus neoformans. The results of the antimicrobial assay showed that the presence of two amidic groups usually enhances antimycotic activity.