Isbell G, Levin B
Department of Medical Oncology, University of Texas, MD Anderson Cancer Center, Houston.
Gastroenterol Clin North Am. 1988 Dec;17(4):773-91.
Chronic ulcerative colitis is an idiopathic inflammatory disease of the colon associated with an increased incidence of colorectal cancer. Colonoscopy with biopsy for mucosal dysplasia (precancer) can identify individuals with ulcerative colitis who are at increased risk for colorectal cancer. Identification of high-risk individuals can be used to guide clinical decisions regarding the timing and appropriateness of prophylactic colectomy.
慢性溃疡性结肠炎是一种与结直肠癌发病率增加相关的结肠特发性炎症性疾病。通过结肠镜检查并取活检以检测黏膜发育异常（癌前病变），可以识别出溃疡性结肠炎患者中患结直肠癌风险增加的个体。识别高危个体可用于指导有关预防性结肠切除术时机和适宜性的临床决策。
