College of Chemistry, Nankai University, No. 94 of Weijin Road, Tianjin 300071, China.
Analyst. 2019 Mar 11;144(6):1916-1922. doi: 10.1039/c8an01895b.
Antibiotics have been noted as an important class of emerging contaminants in the environment. Metal-organic frameworks (MOFs), which have been intensely investigated as a novel kind of sensing material, have been tentatively applied to the detection of antibiotics in recent years. In this work, a nanoscale MOF (In-sbdc) with a strong (quantum yield = 13%) and stable emission in water was synthesized. With its effective spectral overlap with tetracyclines, adsorption preconcentration and the usage of a masking agent, In-sbdc gave sensitive responses to a series of tetracycline antibiotics (tetracycline, chlorotetracycline and oxytetracycline) with detection limits of 0.28-0.30 μM, but another eight tested kinds of antibiotics did not cause a remarkable change in its emission (<10% of the response caused by an equal amount of tetracyclines). This MOF-based sensing system was successfully applied to tetracyclines detection in a series of actual water and food samples.
抗生素已被认为是环境中一类重要的新兴污染物。金属-有机骨架（MOFs）作为一种新型的传感材料受到了广泛的研究，近年来已被初步应用于抗生素的检测。在这项工作中，合成了一种纳米级 MOF（In-sbdc），它在水中具有强（荧光量子产率 = 13%）和稳定的发射。由于与四环素具有有效的光谱重叠、吸附预浓缩以及使用掩蔽剂，In-sbdc 对一系列四环素类抗生素（四环素、金霉素和土霉素）表现出敏感的响应，检测限为 0.28-0.30 μM，而另外八种测试的抗生素则不会引起其发射的显著变化（<四环素引起的响应的 10%）。这种基于 MOF 的传感系统已成功应用于一系列实际水样和食品样中四环素的检测。
