Department of Life Science and Chemistry, Graduate School of Natural Science and Technology, Gifu University, 1-1 Yanagido, Gifu 501-1193, Japan.
Chem Commun (Camb). 2019 Feb 7;55(13):1959-1962. doi: 10.1039/c8cc09345h.
Introducing a desired stimuli-responsive function into catalytically active biomacromolecules is potentially useful in developing molecular tools for various bio-applications. In this paper, we discuss the development of a stimuli-responsive DNAzyme (catalytic deoxyribozyme) capable of displaying Boolean logic-gate responses.
将期望的刺激响应功能引入催化活性的生物大分子中,对于开发各种生物应用的分子工具可能是有用的。在本文中,我们讨论了一种能够显示布尔逻辑门响应的刺激响应 DNA 酶(催化核酶)的开发。