Morita K
First Department of Surgery, Kyoto University School of Medicine, Japan.
Nihon Geka Gakkai Zasshi. 1988 Dec;89(12):1957-64.
Changes of portal blood flow in patients with early dumping syndrome and those with oxyhyperglycemia were determined after oral ingestion of 300ml of 25% glucose solution by a linear-type B mode electroscanner and pulsed Doppler flowmeter. In normal volunteers, the portal blood flow increased slowly to the peak level of 201% of fasting value at 40 minutes. The portal blood flow in postgastrectomy patients reached the peak value more quickly, with the peak level of 245% at 10 minutes in patients with the early dumping syndrome, and of 172% at 15 minutes in patients without the syndrome. The portal blood flow in patients with early dumping syndrome was significantly greater than that without the syndrome. Patients with early dumping syndrome had characteristic symptoms such as general malaise, cold sweat, nausea, abdominal pain, diarrhea in accordance with increased portal blood flow. Patients with high grade oxyhyperglycemia (peak blood sugar after 75g OGTT greater than 250mg/dl) had significantly higher portal blood flow and peripheral blood sugar than those with low grade oxyhyperglycemia (peak blood sugar less than 250mg/dl) without difference in IRI between the two groups.
采用线阵B型超声扫描仪和脉冲多普勒流量计，在口服300ml 25%葡萄糖溶液后，测定早期倾倒综合征患者和血糖过高患者的门静脉血流变化。在正常志愿者中，门静脉血流在40分钟时缓慢增加至空腹值的201%的峰值水平。胃切除术后患者的门静脉血流达到峰值的速度更快，早期倾倒综合征患者在10分钟时峰值水平为245%，无该综合征患者在15分钟时峰值水平为172%。早期倾倒综合征患者的门静脉血流明显高于无该综合征患者。早期倾倒综合征患者伴有全身不适、冷汗、恶心、腹痛、腹泻等特征性症状，与门静脉血流增加有关。高血糖患者（75g口服葡萄糖耐量试验后血糖峰值大于250mg/dl）的门静脉血流和外周血糖明显高于低血糖患者（血糖峰值小于250mg/dl），两组间胰岛素释放指数无差异。
