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[(生长抑素(SS - 14)对胃部分切除术后患者早期倾倒反应的影响)]

[(Influence of somatostatin (SS-14) on early dumping reaction in patients after partial gastrectomy) ].

作者信息

Mörz R, Prager J, Pointner H

出版信息

Z Gastroenterol. 1982 Jun;20(6):299-304.

PMID:6126965
Abstract

In seven patients suffering from early dumping syndrome after partial gastrectomy (Billroth II operation) an early dumping reaction was provoked by 100 g dextrose per os and the influence of somatostatin-14 (SS-14) infusion on clinical appearance of dumping syndrome was evaluated. SS-14 in contrast to the control trial resulted in total suppression of insulin release and slightly delayed and lowered increase of blood glucose which was not statistically significant, but with SS-14 there was no change in clinical symptoms of dumping reaction and compared to the control test no significant difference was found between the decrease of blood pressure, the increase of pulse frequency, the small increase of hematocrit and plasma free fatty acids.

摘要

在7例接受部分胃切除术(毕Ⅱ式手术)后出现早期倾倒综合征的患者中,经口服100克葡萄糖诱发早期倾倒反应,并评估了生长抑素-14(SS-14)输注对倾倒综合征临床表现的影响。与对照试验相比,SS-14导致胰岛素释放完全受到抑制,血糖升高略有延迟且升高幅度降低,这在统计学上无显著意义,但使用SS-14时倾倒反应的临床症状没有变化,与对照试验相比,血压下降、脉搏频率增加、血细胞比容和血浆游离脂肪酸略有增加之间均未发现显著差异。

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