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在斋月禁食期间发生糖尿病酮症酸中毒的几率:一项为期 10 年的单中心回顾性研究。

The incidence of diabetic ketoacidosis during Ramadan fasting: A 10-year single-centre retrospective study.

机构信息

Internal Medicine Residency Program, Institute of Education, Sheikh Khalifa Medical City, Abu Dhabi, United Arab Emirates; Division of Endocrinology, Institute of Medicine, Sheikh Khalifa Medical City, Abu Dhabi, United Arab Emirates.

Division of Endocrinology, Institute of Medicine, Sheikh Khalifa Medical City, Abu Dhabi, United Arab Emirates; Department of Medicine, Dubai Medical College, Dubai, United Arab Emirates.

出版信息

Diabetes Res Clin Pract. 2019 Apr;150:296-300. doi: 10.1016/j.diabres.2019.01.018. Epub 2019 Jan 24.

DOI:10.1016/j.diabres.2019.01.018
PMID:30685349
Abstract

CONTEXT

There has been an increased interest in the potential metabolic derangements and acute complications of diabetes related to the Muslims' fasting during the month of Ramadan.

OBJECTIVES

We compared the incidence of admissions due to diabetic ketoacidosis (DKA) during Ramadan with the admissions during other months.

METHODS

This is a retrospective electronic database and chart review study that included all Muslims who were admitted with DKA to Sheikh Khalifa Medical City in Abu Dhabi, United Arab Emirates. We explored the relationship of admissions to Ramadan over ten years (2005-2014).

RESULTS

There were 432 episodes of DKA involving 283 patients. Of these, 370 episodes (85.6%) involved 231 patients (81.6%) with type 1 diabetes. The number of admission episodes was not different during Ramadan from the average calendar month [3.6 ± 2.6 (Range 0-15) episodes/month versus 3.3 ± 2.1 (Range 1-7) episodes/month respectively, P = 0.77]. No recurrences of admissions were observed during Ramadan. There was a non-significant numerical tendency for more episodes in March and September (4.6 episodes for both) and fewer episodes in July (2.6 episodes) than other months; P values were 0.06; 0.13, and 0.32 respectively. This seasonality was not related to the month of Ramadan.

CONCLUSIONS

The present study confirmed that DKA admissions during Ramadan were not significantly higher than the average monthly admissions over ten years. Seasonality trends were not related to Ramadan.

摘要

背景

人们对与伊斯兰教斋月期间禁食相关的糖尿病潜在代谢紊乱和急性并发症越来越感兴趣。

目的

我们比较了斋月期间因糖尿病酮症酸中毒(DKA)住院的发生率与其他月份的住院率。

方法

这是一项回顾性电子数据库和图表回顾研究,包括所有在阿拉伯联合酋长国阿布扎比谢赫·哈利法医疗城因 DKA 住院的穆斯林患者。我们探讨了十年来(2005-2014 年)住院与斋月的关系。

结果

共有 432 例 DKA 患者 283 例。其中,370 例(85.6%)为 231 例(81.6%)1 型糖尿病患者。住院次数在斋月与平均日历月之间无差异[3.6±2.6(范围 0-15)次/月与 3.3±2.1(范围 1-7)次/月,P=0.77]。在斋月期间没有观察到住院次数的再次增加。尽管在三月和九月有更多的住院次数(各 4.6 次),而在七月住院次数更少(2.6 次),但这一趋势无统计学意义;P 值分别为 0.06、0.13 和 0.32。这种季节性与斋月无关。

结论

本研究证实,在斋月期间,DKA 住院率与十年间的平均每月住院率相比没有显著增加。季节性趋势与斋月无关。

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