Department of Pediatrics, Kyung Hee University School of Medicine, Seoul, Korea.
Central Hospice Center, National Cancer Center, Goyang, Korea.
J Korean Med Sci. 2019 Jan 18;34(4):e34. doi: 10.3346/jkms.2019.34.e34. eCollection 2019 Jan 28.
As the aging society progresses, the average age of mothers is also increasing. Advanced maternal age has been known to be associated with perinatal outcomes, as well as birth weight (BW). In this study, we aimed to investigate the perinatal factors associated with low birth weight infants (LBWIs) using birth statistics of the Korean population.
Birth statistics between 1993 and 2016 from the Korean Statistical Information Service were reviewed. We investigated 12,856,614 data points, which included the number of births, BWs, percentage of preterm births and LBWIs, multiple pregnancies, and maternal age.
The proportion of LBWIs delivered by mothers of advanced maternal age has gradually increased since 1993. In addition, the proportion of older mothers (≥ 35 years old) giving birth to LBWIs has increased over the years. Average BW has a negative correlation with the ratio of preterm births, LBW, multiple births, and advanced maternal age. The mean BW also has a negative correlation with maternal age.
This study shows that the average BW continues to decline, and the incidence of LBWIs is increasing in Korea since 1993. This study also revealed that several perinatal factors, including percentage of preterm births, LBWIs, multiple births, and maternal age influence the mean BW. Although this study did not investigate the effects of decreasing mean BW on perinatal health, future research is worth discussing.
随着老龄化社会的发展，母亲的平均年龄也在增加。高龄产妇与围产结局以及出生体重（BW）有关。本研究旨在利用韩国人口的出生统计数据，探讨与低出生体重儿（LBWIs）相关的围产因素。
回顾了 1993 年至 2016 年期间韩国统计信息服务局的出生统计数据。我们调查了 12856614 个数据点，包括出生人数、BW、早产和 LBWIs 的百分比、多胎妊娠和产妇年龄。
自 1993 年以来，由高龄产妇分娩的 LBWIs 的比例逐渐增加。此外，多年来，年龄较大的母亲（≥35 岁）生育 LBWIs 的比例也有所增加。平均 BW 与早产、LBW、多胎妊娠和高龄产妇的比例呈负相关。平均 BW 也与产妇年龄呈负相关。
本研究表明，自 1993 年以来，韩国的平均 BW 持续下降，LBWIs 的发病率呈上升趋势。本研究还表明，包括早产百分比、LBWIs、多胎妊娠和产妇年龄在内的几个围产因素影响平均 BW。虽然本研究没有调查平均 BW 下降对围产健康的影响，但未来的研究值得讨论。
