Guo Zhen-Ni, Sun Xin, Zhao Yingkai, Yan Xiuli, Zhang Ran, Wang Zan, Yang Yi
Clinical Trial and Research Center for Stroke, Department of Neurology, The First Hospital of Jilin University, Changchun, China.
Department of Neurology, The First Hospital of Jilin University, Changchun, China.
Front Neurol. 2019 Jan 10;9:1155. doi: 10.3389/fneur.2018.01155. eCollection 2018.
Cerebral autoregulation is the mechanism by which constant cerebral blood flow is maintained despite changes in arterial blood pressure. In the two presented cases, cerebral autoregulation was impaired in patients with narcolepsy type 1, and both venlafaxine and fluoxetine may have the potential to improve the impaired cerebral autoregulation. A relationship may exist between impaired cerebral autoregulation and neurological symptoms in patients with narcolepsy type 1.
脑自动调节是一种机制，通过该机制，尽管动脉血压发生变化，仍能维持恒定的脑血流量。在这两个病例中，1型发作性睡病患者的脑自动调节功能受损，而文拉法辛和氟西汀都可能有改善受损脑自动调节功能的潜力。1型发作性睡病患者脑自动调节功能受损与神经症状之间可能存在关联。
