Sato Kota, Takahashi Yoshiaki, Yamashita Toru, Takemoto Mami, Hishikawa Nozomi, Jinwei Shang, Ohta Yasuyuki, Abe Koji
Department of Neurology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Japan.
Neurol Int. 2018 Dec 5;10(4):7852. doi: 10.4081/ni.2018.7852.
A 46-year-old woman developed slowly progressive tongue weakness with a pseudohypertrophic change on the right side of her tongue. She subsequently developed weakness in her proximal lower extremities, skin erythema and a sustained increase of muscle enzymes at 11 M after the onset. A biopsy of the quadriceps muscle showed necrotizing myopathy and a skin biopsy showed erythema nodosum. The present case showed characteristic clinical manifestations that may represent a rare variant of sarcoidosis.
一名46岁女性出现缓慢进展的舌肌无力,右侧舌部有假性肥大改变。发病11个月后,她随后出现近端下肢无力、皮肤红斑和肌酶持续升高。股四头肌活检显示坏死性肌病,皮肤活检显示结节性红斑。本病例表现出特征性临床表现,可能代表结节病的一种罕见变异型。