睡眠呼吸障碍与中风：孰因孰果？
Sleep-disordered breathing and stroke: chicken or egg?
作者信息
Alexiev Filip, Brill Anne-Kathrin, Ott Sebastian R, Duss Simone, Schmidt Markus, Bassetti Claudio L
机构信息
University Sleep-Wake-Epilepsy Center (SWEZ), Department of NeurologyUniversity Hospital (Inselspital), Bern, Switzerland.
Department of Pulmonary Medicine, University Hospital (Inselspital), Bern, Switzerland.
出版信息
J Thorac Dis. 2018 Dec;10(Suppl 34):S4244-S4252. doi: 10.21037/jtd.2018.12.66.
Abstract
The bidirectional interaction between sleep-disordered breathing (SDB) and stroke has been the subject of many studies. On the one hand, different forms of SDB, and especially obstructive sleep apnea, increase the risk of stroke either directly or indirectly by influencing other known cardiovascular risk factors such as arterial hypertension and arrhythmias. On the other hand, stroke itself can cause either appearance of SDB, aggravate a pre-existing SDB, or trigger a transition from one type of pathological SDB pattern into another. In this review, we discuss some aspects of this "chicken or egg" relationship.
摘要
睡眠呼吸障碍（SDB）与中风之间的双向相互作用一直是许多研究的主题。一方面，不同形式的SDB，尤其是阻塞性睡眠呼吸暂停，通过影响其他已知的心血管危险因素，如动脉高血压和心律失常，直接或间接地增加中风风险。另一方面，中风本身可导致SDB的出现、加重已有的SDB或引发从一种病理性SDB模式向另一种模式的转变。在本综述中，我们讨论了这种“鸡生蛋还是蛋生鸡”关系的一些方面。
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