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使用羟基磷灰石网片翻修全髋关节置换术后伴血肿的进行性骨质溶解:一例报告

Progressive Osteolysis with Hematoma Following Revision Total Hip Arthroplasty using Hydroxyapatite Mesh: A Case Report.

作者信息

Matsuda Shougo, Kaku Nobuhiro, Tabata Tomonori, Tsumura Hiroshi

机构信息

Department of Orthopaedic Surgery, Faculty of Medicine, Oita University, 1-1 Idaigaoka Hazama-Machi, Yufu City, Oita. Japan.

出版信息

J Orthop Case Rep. 2018 Jul-Aug;8(4):25-28. doi: 10.13107/jocr.2250-0685.1142.

Abstract

INTRODUCTION

Osteolysis around the prosthesis following total hip arthroplasty (THA) is usually expanded slowly in the mid to long term, not progressive in the short term. Hematoma around the prosthesis is a rare phenomenon after a period of 1 year or more after surgery other than metal on metal THA. In addition, there are no studies reporting that hydroxyapatite (HA) itself has a possibility to cause osteolysis or hematoma after THA. This case has a particular disease phenomenon with three unusual factors, such as progressive osteolysis, hematoma, and HA debris in granulation tissue, following revision THA.

CASE REPORT

A 79-year-old woman with pain in the left hip joint underwent a revision THA, using HA mesh and ultra high molecular weight polyethylene fiber cable for impaction bone grafting to fill a bone defect in the proximal femur in 2011. There were no abnormal findings clinically or on radiograph until 2014. Moderate osteolysis was observed at the lesser trochanter and the area distal to the greater trochanter on the radiograph in 2015. The synovial fluid culture was negative. On magnetic resonance imaging examination, the margin showed a low-density shell in both the T1- and T2-weighted images, and the inside was a mosaic mass, with mixed low- and high-density are as extending in a multidirectional manner. During surgery, cystic mass covered with a thick membrane was found around the artificial hip joint, and the inside of the capsule was full of solid and fluid hematoma and dark blood. There was no apparent wear and tear debris of the implant. On pathological examination, evidence of chronic hematoma, granulation tissue, and HA debris, interspersed inside the granulation tissue were observed.

CONCLUSION

We experienced an extremely rare case with osteolysis and hematoma that progressively expanded in a short period of time after revision THA using HA mesh, which seemed to be caused by, crushed HA and resulted in osteolysis accompanied by hematoma. This case revealed that HA it has a possibility to cause osteolysis or hematoma after THA.

摘要

引言

全髋关节置换术(THA)后假体周围的骨溶解在中长期通常进展缓慢,短期内无进展。除金属对金属全髋关节置换术外,术后1年或更长时间后假体周围出现血肿是一种罕见现象。此外,尚无研究报道羟基磷灰石(HA)本身在全髋关节置换术后有引起骨溶解或血肿的可能性。本病例在翻修全髋关节置换术后出现了一种特殊的疾病现象,具有三个不寻常的因素,如进行性骨溶解、血肿和肉芽组织中的HA碎片。

病例报告

一名79岁左侧髋关节疼痛的女性于2011年接受了翻修全髋关节置换术,使用HA网片和超高分子量聚乙烯纤维缆绳进行嵌压植骨以填充股骨近端的骨缺损。直到2014年,临床和影像学检查均未发现异常。2015年,X线片显示小转子及大转子远端区域出现中度骨溶解。滑膜液培养为阴性。在磁共振成像检查中,T1加权和T2加权图像上边缘均显示为低密度壳,内部为镶嵌状肿块,有混合的低密度和高密度区域呈多方向延伸。手术过程中,在人工髋关节周围发现了一个被厚膜覆盖的囊性肿块,囊内充满了固体和液体血肿以及暗红色血液。植入物没有明显的磨损碎片。病理检查发现有慢性血肿、肉芽组织的证据,并且在肉芽组织内部观察到有HA碎片散布。

结论

我们遇到了一例极为罕见的病例,在使用HA网片进行翻修全髋关节置换术后短时间内出现了进行性扩大的骨溶解和血肿,这似乎是由破碎的HA引起的,并导致了伴有血肿的骨溶解。该病例表明,HA在全髋关节置换术后有引起骨溶解或血肿的可能性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9af5/6343563/1339501cdd92/JOCR-8-25-g005.jpg

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