Key Laboratory of Pollution Processes and Environmental Criteria, Ministry of Education, Tianjin Key Laboratory of Environmental Remediation and Pollution Control, College of Environmental Science and Engineering, Nankai University, Tianjin 300350, PR China.
Toxicological Center, University of Antwerp, Universiteitsplein 1, 2610 Wilrijk, Antwerp, Belgium.
Environ Int. 2019 Apr;125:25-32. doi: 10.1016/j.envint.2019.01.018. Epub 2019 Jan 26.
The bioavailability and biomagnification of organophosphate esters (OPEs) were investigated in a food web in the Zhushan Bay of Taihu Lake, China. The organisms included mainly three biological groups: plankton, invertebrates, and fish, which displayed distinctly different compositional profiles of OPEs. In general, the log BAFs (bioaccumulation factor) of OPEs displayed a significant correlation with their log K (octanol-water partitioning coefficient), suggesting that the bioaccumulation was mainly controlled by the hydrophobicity. The log BAFs of the more hydrophobic OPEs in benthic invertebrates were higher than in fish, suggesting that ingesting sediment constituted additional exposure route for benthic invertebrates. The log BSAFs (biota-sediment accumulation factor) in the benthic invertebrates increased with log K in the range of 1.44-5.73 and decreased afterwards. The depressed bioavailability of the highly hydrophobic OPEs was attributed to their strong adsorption to the sediment. The biomagnification potency of OPEs was affected by hydrophobicity of the compounds and biotransformation properties in the organisms at different trophic levels. 2-Ethylhexyl diphenyl phosphate biomagnified in the fish food web of Taihu Lake with a TMF (trophic magnification factor) of 3.61, which was due to the combined results of its relatively high hydrophobicity (log K of 5.73) and decreased metabolism potential in the high-trophic-level fish. The constant metabolism diminished the biomagnification potency of hydrophobic compounds triphenyl phosphate and tricresyl phosphate in this food web.
在中国太湖竺山湾的食物网中研究了有机磷酸酯（OPEs）的生物利用度和生物放大作用。研究的生物主要包括浮游生物、无脊椎动物和鱼类，它们表现出明显不同的 OPEs 组成谱。一般来说，OPEs 的 log BAF（生物累积因子）与它们的 log K（辛醇-水分配系数）呈显著相关，表明生物累积主要受疏水性控制。底栖无脊椎动物中疏水性较高的 OPEs 的 log BAF 高于鱼类，表明摄入沉积物是底栖无脊椎动物的额外暴露途径。底栖无脊椎动物中的 log BSAF（生物-沉积物累积因子）随着 log K 在 1.44-5.73 的范围内增加，随后减少。高度疏水性 OPEs 的生物利用度降低是由于它们与沉积物的强烈吸附。OPEs 的生物放大能力受化合物的疏水性和不同营养级生物体内的生物转化特性的影响。2-乙基己基二苯基磷酸酯在太湖鱼类食物网中具有 3.61 的 TMF（营养级放大因子），这是由于其相对较高的疏水性（log K 为 5.73）和高营养级鱼类中代谢潜力降低的综合结果。恒速代谢降低了疏水性化合物三苯基磷酸酯和三氯甲苯磷酸酯在该食物网中的生物放大能力。
