Academy of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, P. R. China.
College of Life Sciences, Fujian Agriculture and Forestry University, Fuzhou, Fujian, P. R. China.
Luminescence. 2019 May;34(3):308-315. doi: 10.1002/bio.3596. Epub 2019 Jan 28.
Foodborne contaminants widely exist in foods, which can lead to various foodborne diseases and food safety issues. The development of quick, sensitive and universal analytical approaches for foodborne contaminants is imperative. Electrochemiluminescent functional nucleic acids (ECL FNAs)-based sensors are a series of sensing devices using FNAs as the recognition elements and ECL as the transducer. Contributing to the specific recognition ability of FNA and the high sensitivity of ECL, ECL FNA-based sensors are considered to be of great application potential for foodborne contaminants monitoring. This review mainly presents the applications of ECL FNA-based sensors for foodborne contaminants (including microorganisms, mycotoxins, allergens, antibiotics, heavy metal ions, pesticides and some illegal additives). In general, the application of ECL FNA-based sensors in the field of food analysis is just in its infancy. Although there are several limitations and challenges, it is envisaged that ECL FNA-based sensors will have broad prospects for food analysis in the future.
食源性污染物广泛存在于食品中，可能导致各种食源性疾病和食品安全问题。因此，开发快速、灵敏和通用的食源性污染物分析方法势在必行。基于电化学发光功能核酸（ECL FNAs）的传感器是一系列利用 FNAs 作为识别元件、ECL 作为换能器的传感装置。基于 ECL FNAs 的传感器结合了 FNA 的特异性识别能力和 ECL 的高灵敏度，被认为在食源性污染物监测方面具有巨大的应用潜力。本综述主要介绍了基于 ECL FNAs 的传感器在食源性污染物（包括微生物、真菌毒素、过敏原、抗生素、重金属离子、农药和一些非法添加剂）监测方面的应用。总的来说，基于 ECL FNAs 的传感器在食品分析领域的应用还处于起步阶段。尽管存在一些局限性和挑战，但预计基于 ECL FNAs 的传感器在未来的食品分析中具有广阔的前景。
