Saravana-Bawan Samantha, David Elizabeth, Sahgal Arjun, Chow Edward
Division of Interventional Radiology, Sunnybrook Hospital, Toronto, Ontario, Canada.
Division of Radiation Oncology, Sunnybrook Hospital, Toronto, Ontario, Canada.
Ann Palliat Med. 2019 Apr;8(2):168-177. doi: 10.21037/apm.2018.12.04. Epub 2019 Jan 2.
Multiple new options are available in the palliation of bone metastases. Most of these techniques can be used in conjunction with radiation therapy either before or after and are now giving patients who have reached dose limitations new options. These techniques can also be used with vertebroplasty (VP) to increase structural stability post tumor ablation. Localized percutaneous treatment in the bone such as thermal [radiofrequency ablation (RFA)] and light [photodynamic therapy (PDT)] have been used to destroy tumor prior to injection with cement. This educational review will discuss the safety profile, technique and indications for emerging technology in the area of locoregional treatment of bone metastases in conjunction with vertebral augmentation. It will not delve comprehensively into conventional lines of treatment where indications and outcomes have already been well established.
在骨转移瘤的姑息治疗中有多种新的选择。这些技术大多可在放疗前后联合使用，为已达到剂量限制的患者提供了新的选择。这些技术也可与椎体成形术（VP）联合使用，以提高肿瘤消融后的结构稳定性。骨局部的经皮治疗，如热消融[射频消融（RFA）]和光消融[光动力疗法（PDT）]，已被用于在注射骨水泥前破坏肿瘤。本综述将讨论与椎体强化联合用于骨转移瘤局部区域治疗的新兴技术的安全性、技术和适应证。本文不会全面深入探讨传统治疗方法，因为其适应证和疗效已经得到充分确立。
