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使用新型软组织愈合指数评估牙龈切除术后低强度激光照射后的愈合情况:一项随机、双盲、半口对照临床试验研究

Assessment of healing following low-level laser irradiation after gingivectomy operations using a novel soft tissue healing index: A randomized, double-blind, split-mouth clinical pilot study.

作者信息

Lingamaneni Shreya, Mandadi Lohith Reddy, Pathakota Krishnajaneya Reddy

机构信息

Private Practice, Family Dental Care, Hyderabad, Telangana, India.

Department of Periodontics, Sri Sai College of Dental Surgery, Hyderabad, Telangana, India.

出版信息

J Indian Soc Periodontol. 2019 Jan-Feb;23(1):53-57. doi: 10.4103/jisp.jisp_226_18.

DOI:10.4103/jisp.jisp_226_18
PMID:30692744
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6334552/
Abstract

BACKGROUND

Lasers have become a part of modern dentistry since the past three decades. A wide-ranging assortment of lasers is being used in periodontology for both soft and hard tissue surgical procedures. Regardless of the frequent practice of using these well-known surgical lasers, there is another lesser familiar class of lasers called the low-level lasers. The main doctrine behind using low-level laser therapy (LLLT) is centered on the biostimulation, or the biomodulation effect, which relies on the dexterity of low-intensity laser energy when irradiated at a specific wavelength, is able to modify cellular activities (increase in cell metabolism and fibroblast and keratinocyte proliferation).

AIM

The aim of the present study was to investigate the adjunctive use of LLLT on gingival healing after gingivectomy procedures.

MATERIALS AND METHODS

Ten systemically healthy patients requiring gingivectomy or gingivoplasty procedures bilaterally in either the maxillary or mandibular teeth were included in the study. After surgical intervention, a diode laser (810 nm) was randomly activated to one side of the operated area while other side did not receive any treatment and served as the control. The healing index given by Landry . was used to evaluate the soft tissue healing immediately postsurgery and at the 3 day, 1 week, and 2 weeks postoperatively. After the follow-up period, results were analyzed using appropriate statistical tests.

RESULTS

There was no statistically significant difference observed in the surface epithelialization between both groups on the 3 and 7-postoperative days, but highly significant differences were observed on the 14 day.

CONCLUSION

Within the confines of this pilot study, the outcomes have indicated that gingival wound healing may be improved using LLLT after gingivectomy and gingivoplasty operations.

摘要

背景

在过去三十年里,激光已成为现代牙科的一部分。各种各样的激光被用于牙周病学的软组织和硬组织外科手术。尽管这些知名的外科激光被频繁使用,但还有另一类不太为人熟悉的激光,即低强度激光。使用低强度激光疗法(LLLT)背后的主要理论集中在生物刺激或生物调节作用上,这依赖于低强度激光能量在特定波长照射时能够改变细胞活动(增加细胞代谢以及成纤维细胞和角质形成细胞增殖)的灵活性。

目的

本研究的目的是调查LLLT在牙龈切除术后牙龈愈合中的辅助应用。

材料和方法

本研究纳入了10名全身健康、需要在上颌或下颌牙齿双侧进行牙龈切除术或牙龈成形术的患者。手术干预后,将二极管激光(810纳米)随机应用于手术区域的一侧,而另一侧不接受任何治疗作为对照。采用兰德里给出的愈合指数来评估术后即刻以及术后第3天、1周和2周时的软组织愈合情况。随访期结束后,使用适当的统计检验对结果进行分析。

结果

术后第3天和第7天,两组之间的表面上皮形成没有观察到统计学上的显著差异,但在第14天观察到了高度显著的差异。

结论

在本初步研究的范围内,结果表明在牙龈切除术和牙龈成形术后使用LLLT可能会改善牙龈伤口愈合。

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