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本文引用的文献

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Multiple Sclerosis.多发性硬化症
N Engl J Med. 2018 Jan 11;378(2):169-180. doi: 10.1056/NEJMra1401483.
2
Validity of the timed 25-foot walk as an ambulatory performance outcome measure for multiple sclerosis.25英尺定时步行作为多发性硬化症动态表现结果测量指标的有效性。
Mult Scler. 2017 Apr;23(5):704-710. doi: 10.1177/1352458517690823. Epub 2017 Feb 16.
3
The Nine-Hole Peg Test as a manual dexterity performance measure for multiple sclerosis.九孔插板测试作为多发性硬化症手部灵巧性的一项性能指标。
Mult Scler. 2017 Apr;23(5):711-720. doi: 10.1177/1352458517690824. Epub 2017 Feb 16.
4
Binocular low-contrast letter acuity and the symbol digit modalities test improve the ability of the Multiple Sclerosis Functional Composite to predict disease in pediatric multiple sclerosis.双眼低对比度字母视力和符号数字模态测试提高了多发性硬化功能综合指数预测儿科多发性硬化疾病的能力。
Mult Scler Relat Disord. 2016 Nov;10:73-78. doi: 10.1016/j.msard.2016.08.012. Epub 2016 Aug 26.
5
A one-year follow-up study of the Symbol Digit Modalities Test (SDMT) and the Paced Auditory Serial Addition Test (PASAT) in relapsing-remitting multiple sclerosis: an appraisal of comparative longitudinal sensitivity.复发缓解型多发性硬化症中符号数字模式测验（SDMT）和听觉序列加法测验（PASAT）的一年随访研究：比较纵向敏感性评估
BMC Neurol. 2015 Mar 22;15:40. doi: 10.1186/s12883-015-0296-2.
6
The epidemiology of multiple sclerosis: insights to disease pathogenesis.多发性硬化症的流行病学：对疾病发病机制的见解
Handb Clin Neurol. 2014;122:231-66. doi: 10.1016/B978-0-444-52001-2.00010-8.
7
Timed 25-foot walk: direct evidence that improving 20% or greater is clinically meaningful in MS.25 英尺计时行走测试：在多发性硬化症中，提高 20%或更多具有临床意义的直接证据。
Neurology. 2013 Apr 16;80(16):1509-17. doi: 10.1212/WNL.0b013e31828cf7f3. Epub 2013 Mar 27.
8
Multiple sclerosis.多发性硬化症
Lancet. 2008 Oct 25;372(9648):1502-17. doi: 10.1016/S0140-6736(08)61620-7.
9
Temporal trends in the incidence of multiple sclerosis: a systematic review.多发性硬化症发病率的时间趋势：一项系统综述。
Neurology. 2008 Jul 8;71(2):129-35. doi: 10.1212/01.wnl.0000316802.35974.34.
10
A comprehensive review of the Paced Auditory Serial Addition Test (PASAT).对节律性听觉系列加法测验（PASAT）的全面综述。
Arch Clin Neuropsychol. 2006 Jan;21(1):53-76. doi: 10.1016/j.acn.2005.07.006. Epub 2005 Nov 14.

多发性硬化功能综合评分

Multiple Sclerosis Functional Composite.

作者信息

Demir Serkan

机构信息

Sultan Abdülhamid Han Research and Training Hospital, Neurology Clinic, İstanbul, Turkey.

出版信息

Noro Psikiyatr Ars. 2018;55(Suppl 1):S66-S68. doi: 10.29399/npa.23349.

DOI:10.29399/npa.23349
PMID:30692860
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6278630/
Abstract

Functional disorders due to multiple sclerosis are evaluated using rating scales. EDSS is a scant which is very inadequate in evaluating cognitive functions, is significantly limited in evaluating upper extremity functions and is highly difficult to repeat. Multiple Sclerosis Functional Composite (MSFC) is considered as a test that has been proposed in recent years in MS clinical trials and can overcome these negative features of EDSS. Three primary assessment methods were suggested for MSFC (9): 1) 25-step walking, 2) 9-Hole Peg test (9-HPT), and 3) Paced Auditory Serial Addition Test-3 (PASAT-3).

摘要

多发性硬化症所致功能障碍通过评定量表进行评估。扩展残疾状态量表（EDSS）是一种评估方法，在评估认知功能方面非常不足，在评估上肢功能方面有显著局限性，且很难重复使用。多发性硬化功能复合量表（MSFC）被认为是近年来在多发性硬化症临床试验中提出的一种测试方法，它可以克服EDSS的这些负面特征。MSFC建议采用三种主要评估方法（9）：1）25步步行测试，2）9孔插钉测试（9-HPT），以及3）听觉节律性连续加法测试-3（PASAT-3）。