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非增强T1加权磁共振成像在经皮冠状动脉介入治疗中的临床应用:一例报告。

Clinical utility of non-contrast T1-weighted magnetic resonance imaging in percutaneous coronary intervention: A case report.

作者信息

Oshita Akira, Kawakami Hideo, Kito Katsumi, Kono Yusuke, Miyoshi Toru, Matsuoka Hiroshi

机构信息

Department of Cardiology, Ehime Prefectural Imabari Hospital, Imabari, Japan.

Department of Pathology, Ehime Prefectural Central Hospital, Matsuyama, Japan.

出版信息

J Cardiol Cases. 2018 Oct 17;19(1):9-11. doi: 10.1016/j.jccase.2018.08.008. eCollection 2019 Jan.

Abstract

Coronary high-intensity plaques (HIPs) visualized by non-contrast T1-weighted imaging (T1WI) in cardiac magnetic resonance (CMR) are associated with slow-flow phenomena during percutaneous coronary intervention (PCI). We report a case of a 52-year-old man who had undergone left anterior descending artery stent implantation for unstable angina 5 years previously. He underwent CMR imaging for screening of vulnerable plaques. A lesion in the proximal right coronary artery showed HIP on non-contrast T1WI. Invasive coronary angiography showed progressive stenosis and PCI was performed. Non-contrast T1WI indicated a high risk for a slow-flow phenomenon. A distal protection device (Parachute™ (Tri-Med, Osaka, Japan)) was deployed at the distal site of the lesion. Following balloon dilation, a filter no-reflow phenomenon developed. Coronary flow was improved with removal of the Parachute™ after debris aspiration. Histological examination revealed aspirated debris composed of white thrombi, foamy macrophages, and cholesterol crystals. < Although optimal medical therapy has improved the prognosis of patients with acute coronary syndrome, recurrent major adverse cardiovascular events occur in a substantial proportion of patients. Non-contrast T1-weighted imaging is a valuable tool for use in screening of vulnerable plaque and prediction of slow-flow phenomenon during percutaneous coronary intervention.>.

摘要

通过心脏磁共振成像(CMR)中的非对比T1加权成像(T1WI)可视化的冠状动脉高强度斑块(HIP)与经皮冠状动脉介入治疗(PCI)期间的慢血流现象相关。我们报告了一例52岁男性患者,该患者5年前因不稳定型心绞痛接受了左前降支动脉支架植入术。他接受了CMR成像以筛查易损斑块。右冠状动脉近端的一个病变在非对比T1WI上显示为HIP。有创冠状动脉造影显示病变进展,遂进行了PCI。非对比T1WI提示存在慢血流现象的高风险。在病变远端部位部署了一个远端保护装置(Parachute™(Tri-Med,日本大阪))。球囊扩张后,出现了滤器无复流现象。在吸出碎片后移除Parachute™后,冠状动脉血流得到改善。组织学检查显示吸出的碎片由白色血栓、泡沫巨噬细胞和胆固醇晶体组成。<尽管最佳药物治疗改善了急性冠状动脉综合征患者的预后,但相当一部分患者仍会发生复发性重大不良心血管事件。非对比T1加权成像对于筛查易损斑块和预测经皮冠状动脉介入治疗期间的慢血流现象是一种有价值的工具。>

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Update in pharmacological management of coronary no-reflow phenomenon.冠状动脉无复流现象的药物治疗进展
Cardiovasc Hematol Agents Med Chem. 2012 Sep;10(3):256-64. doi: 10.2174/187152512802651024.

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