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快速准确地生成嵌入皮肤的血管图像。

Fast and precise image generation of blood vessels embedded in skin.

机构信息

Institute for Laser Technologies in Medicine and Metrology, Ulm, Germany.

出版信息

J Biomed Opt. 2019 Jan;24(1):1-9. doi: 10.1117/1.JBO.24.1.015002.

Abstract

A software for fast rendering the visual appearance of a blood vessel located in human skin was developed based on a numerical solution of the radiative transfer equation. The user can specify geometrical properties, such as the depth and the diameter of the vessel, and physiological properties, such as the oxygen saturation of the vessel or the blood concentration in the skin. From these data, the spatially and spectrally resolved reflectance from the skin containing the blood vessel is calculated via Monte Carlo simulations, by which a two-dimensional image is generated. The short calculation time of about a second is achieved by precalculating and storing the spatially resolved reflectance for a variety of combinations of the optical and geometrical properties. This concept gives the user the opportunity to rapidly explore the influence of the physiological and geometrical properties of the investigated blood vessel on its visual appearance. The correctness of the lookup table was validated by comparison with independent Monte Carlo simulations. Rendering examples of different blood vessels in human skins are given. The current version of the software can be downloaded at https://www.ilm-ulm.de/software.

摘要

开发了一种基于辐射传递方程数值解的软件,用于快速呈现位于人体皮肤内的血管的视觉外观。用户可以指定血管的几何形状,如深度和直径,以及生理特性,如血管的氧饱和度或皮肤中的血液浓度。根据这些数据,通过蒙特卡罗模拟计算包含血管的皮肤的空间和光谱分辨反射率,生成二维图像。通过预先计算和存储各种光学和几何特性组合的空间分辨反射率,实现了约 1 秒的短计算时间。该概念使用户有机会快速探索所研究血管的生理和几何特性对其视觉外观的影响。通过与独立的蒙特卡罗模拟进行比较,验证了查找表的正确性。给出了不同血管在人体皮肤中的渲染示例。该软件的当前版本可在 https://www.ilm-ulm.de/software 下载。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/48bd/6985685/5c5abe7f84d4/JBO-024-015002-g001.jpg

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