Org Lett. 2019 Feb 15;21(4):1116-1120. doi: 10.1021/acs.orglett.9b00034. Epub 2019 Jan 29.
An efficient synthesis of quinolines, pyrimidines, quinoxalines, pyrroles, and aminomethylated aromatic compounds catalyzed by a well-defined Re(I) PNP pincer complex is described. All reactions proceed with liberation of dihydrogen and elimination of water. Under optimized reaction conditions a wide range of organic functional groups are tolerated. This study demonstrates that rhenium catalysts are performing extremely well in dehydrogenative processes with considerably lower catalyst loadings and shorter reaction times when compared to analogous Mn(I) complexes.
本文描述了一种由结构明确的 Re(I)PNP 钳形配合物催化的喹啉、嘧啶、喹喔啉、吡咯和氨甲基化芳香族化合物的高效合成方法。所有反应都伴随着氢气的释放和水的消除。在优化的反应条件下，广泛的有机官能团都能被容忍。该研究表明，与类似的 Mn(I)配合物相比，铼催化剂在脱氢过程中表现出色，催化剂负载量更低，反应时间更短。
