Kharseeva G G, Voronina N A, Gasretova T D, Sylka O I, Tyukdvkina S Yu
Zh Mikrobiol Epidemiol Immunobiol. 2017 Mar(2):3-8.
Study the frequency of occurrence of antibiotics resistant strains of various species of Corynebacterium non diptheriae.
C.pseudodiphtheriticum, C.pseudo- tuberculosis, C.xerosis, C.amycolatum, C.striatum, C. ulcerans strains isolated from patients with pathologies of respiratory and urogenital tract, as well as individuals taking prophylaxis ex- amination were used. Sensitivity to antibacterial preparations was determined by the serial dilution method.
The highest number of Coryniebacterium non diptheriae strains dis- played resistance to benzylpenicillin (54.8%) and lincomycin (50.7%), and lowest - to cefotaxime, cefazolin (6.8%) and vancomycin (13.7%). The highest number of antibiotics resistant strains were detected among members of C.pseudotuberculosis (100%), C.xerosis (96.0%) and C. pseudodiphtheriticum (81.0%) species. Polyresistant strains were detected most frequently among C.xerosis, C.amycolatum and C.striatum species. Strains of Corynebacterium non diptheriae most frequently displayed resistance to 1 or 2 antibacterial preparations (24.7%), less frequently - to 3 (20.5%); 4 (13.7%), 5 (4.1%) and 6 (1.4%) preparations.
The amount of antibiotics resistant strains of Cdrynebacterium non diptheriae is large (89.0%) and non-similar in various species.
研究非结核分枝杆菌各菌种抗生素耐药菌株的发生率。
使用从呼吸道和泌尿生殖道疾病患者以及接受预防性检查的个体中分离出的假结核棒状杆菌、假结核分枝杆菌、干燥棒状杆菌、无枝菌酸棒状杆菌、纹带棒状杆菌、溃疡棒状杆菌菌株。采用系列稀释法测定对抗菌制剂的敏感性。
非结核分枝杆菌菌株对苄青霉素（54.8%）和林可霉素（50.7%）的耐药率最高，而对头孢噻肟、头孢唑林（6.8%）和万古霉素（13.7%）的耐药率最低。在假结核分枝杆菌（100%）、干燥棒状杆菌（96.0%）和假结核棒状杆菌（81.0%）菌种成员中检测到的抗生素耐药菌株数量最多。在干燥棒状杆菌、无枝菌酸棒状杆菌和纹带棒状杆菌菌种中最常检测到多重耐药菌株。非结核分枝杆菌菌株最常对1种或2种抗菌制剂耐药（24.7%），对3种（20.5%）、4种（13.7%）、5种（4.1%）和6种（1.4%）制剂耐药的情况较少。
非结核分枝杆菌抗生素耐药菌株数量众多（89.0%），且各菌种情况不同。
