Henriksen L O, Petersen F, Nielsen K R, Agger P
Department of Surgery, Ringsted Hospital, Denmark.
Int Urol Nephrol. 1988;20(5):497-500. doi: 10.1007/BF02550610.
A double-blind study of the short-term effects of intravesically administered emepronium bromide (Cetiprin) versus placebo on bladder spasms after transurethral prostatectomy was done in 40 male patients. In the Cetiprin group there was a significant decline in the need for analgesia, and significantly fewer catheter problems. The use of intravesically instilled Cetiprin is recommended only in cases of severe postoperative bladder spasms.
对40名男性患者进行了一项双盲研究，比较经膀胱给予溴化依米普明（西替普林）与安慰剂对经尿道前列腺切除术后膀胱痉挛的短期影响。在西替普林组中，镇痛需求显著下降，导管问题也明显减少。仅在严重的术后膀胱痉挛病例中建议使用经膀胱灌注西替普林。
