Walter S, Hansen J, Hansen L, Maegaard E, Meyhoff H H, Nordling J
Br J Urol. 1982 Jun;54(3):249-51. doi: 10.1111/j.1464-410x.1982.tb06968.x.
The effect of the anticholinergic agent, emepronium bromide (Cetiprin), was studied in a double blind crossover study of a group of elderly patients with urinary incontinence and uninhibited bladder contractions during cystometry. There was no statistically significant difference between the subjective effect of emepronium bromide and that of placebo, and no change in the cystometric parameters. The overall subjective cure or improvement rate was 79%. The effect of anticholinergic drugs in the treatment of urinary incontinence in elderly patients with uninhibited bladder contractions might to some extent be due to an improvement in the patients' understanding and acceptance of the bladder disorders.
在一项双盲交叉研究中，对一组患有尿失禁且在膀胱测压时有膀胱无抑制性收缩的老年患者，研究了抗胆碱能药物溴化依米普明（Cetiprin）的效果。溴化依米普明的主观效果与安慰剂之间无统计学显著差异，且膀胱测压参数无变化。总体主观治愈率或改善率为79%。抗胆碱能药物在治疗患有膀胱无抑制性收缩的老年患者尿失禁方面的效果，在某种程度上可能归因于患者对膀胱疾病理解和接受程度的改善。
