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建议高危患者进行切除术：在患者风险的背景下重新审视核心活检中乳头状瘤的诊断。

Excision recommended in high-risk patients: Revisiting the diagnosis of papilloma on core biopsy in the context of patient risk.

机构信息

Penn State College of Medicine, Hershey, Pennsylvania.

Department of Radiology, Division of Breast Imaging, Penn State Health, Milton S. Hershey Medical Center, Hershey, Pennsylvania.

出版信息

Breast J. 2019 Mar;25(2):232-236. doi: 10.1111/tbj.13200. Epub 2019 Jan 30.

DOI:10.1111/tbj.13200
PMID:30697873
Abstract

We investigate the clinical history, past medical history, and risk status in women with benign intraductal papillomas(IDP). We observed an upgrade rate of 3.9% to ductal carcinoma in situ (DCIS) and upgrade rate of 10.7% to a high-risk lesion. Prior or concurrent atypia or cancer and high-risk status had a significant increase risk of upgrade. Surgical excision of papillomas is recommended especially in high-risk patients and women with concurrent or history of atypia or malignancy.

摘要

我们研究了患有良性导管内乳头状瘤（IDP）的女性的临床病史、既往病史和风险状况。我们观察到导管原位癌（DCIS）的升级率为 3.9%，高危病变的升级率为 10.7%。既往或同时存在不典型增生或癌症以及高危状态显著增加了升级的风险。建议对乳头状瘤进行手术切除，特别是对高危患者以及同时存在或有不典型增生或恶性肿瘤病史的女性。

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Excision recommended in high-risk patients: Revisiting the diagnosis of papilloma on core biopsy in the context of patient risk.建议高危患者进行切除术：在患者风险的背景下重新审视核心活检中乳头状瘤的诊断。
Breast J. 2019 Mar;25(2):232-236. doi: 10.1111/tbj.13200. Epub 2019 Jan 30.
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引用本文的文献

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Cureus. 2024 Feb 22;16(2):e54716. doi: 10.7759/cureus.54716. eCollection 2024 Feb.
2
Does previous history of cancer or atypia predict histologic upgrade for pure intraductal papillomas diagnosed via core biopsy? A study of 490 cases at a single institution.既往癌症或非典型病史是否能预测单纯导管内乳头状瘤经核心活检诊断后的组织学升级？单中心 490 例研究。
Cancer Rep (Hoboken). 2022 Mar;5(3):e1481. doi: 10.1002/cnr2.1481. Epub 2021 Nov 2.
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Papillary neoplasms of the breast including upgrade rates and management of intraductal papilloma without atypia diagnosed at core needle biopsy.
乳腺的乳头瘤性肿瘤，包括在核心针活检时诊断为非典型性的导管内乳头状瘤的升级率和处理。
Mod Pathol. 2021 Jan;34(Suppl 1):78-93. doi: 10.1038/s41379-020-00706-5. Epub 2020 Oct 26.
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Benign Breast Intraductal Papillomas Without Atypia at Core Needle Biopsies: Is Surgical Excision Necessary?良性乳腺导管内乳头状瘤，核心针活检无非典型性：是否需要手术切除？
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The genetic architecture of breast papillary lesions as a predictor of progression to carcinoma.作为癌进展预测指标的乳腺乳头状病变的遗传结构
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