School of Biotechnology and Health Sciences, Wuyi University, Jiangmen, Guangdong Province 529090, China.
Chem Commun (Camb). 2019 Feb 14;55(15):2170-2173. doi: 10.1039/c9cc00128j.
Semi-hydrogenation of alkynes is one of the most widely used methods for obtaining alkenes in laboratory preparation and in industry. Transition metal catalysts have been extensively studied for this transformation, but the tolerance of functional groups, such as pyridine, -OH, -NH2, -Bpin, and halides, and the toxicity of the trace amount of transition metal catalysts are still highly challenging. In this study, we report a general and robust strategy to achieve the semi-hydrogenation of alkynes using inexpensive and commercially available xanthate as the mediator. Mechanism studies support a non-radical process and H2O acts as the hydrogen donor.
炔烃的半氢化是实验室制备和工业中获得烯烃最广泛使用的方法之一。对于这种转化，过渡金属催化剂已经被广泛研究，但是官能团如吡啶、-OH、-NH2、-Bpin 和卤化物的耐受性以及痕量过渡金属催化剂的毒性仍然极具挑战性。在这项研究中，我们报告了一种使用廉价且市售的黄原酸盐作为介体实现炔烃半氢化的通用且稳健的策略。机理研究支持非自由基过程，并且 H2O 充当氢供体。
