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第一排（3d）过渡金属催化剂催化炔烃的立体选择性半氢化反应

Stereoselective Semi-Hydrogenations of Alkynes by First-Row (3d) Transition Metal Catalysts.

作者信息

Gregori Bernhard J, Schmotz Mattis-Ole W S, Jacobi von Wangelin Axel

机构信息

Dept. of Chemistry University of Hamburg Martin Luther King Pl 6 20146 Hamburg Germany.

出版信息

ChemCatChem. 2022 Oct 21;14(20):e202200886. doi: 10.1002/cctc.202200886. Epub 2022 Sep 15.

DOI:10.1002/cctc.202200886
PMID:36632425
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9825939/
Abstract

The chemo- and stereoselective semi-hydrogenation of alkynes to alkenes is a fundamental transformation in synthetic chemistry, for which the use of precious 4d or 5d metal catalysts is well-established. In mankind's unwavering quest for sustainability, research focus has considerably veered towards the 3d metals. Given their high abundancy and availability as well as lower toxicity and noxiousness, they are undoubtedly attractive from both an economic and an environmental perspective. Herein, we wish to present noteworthy and groundbreaking examples for the use of 3d metal catalysts for diastereoselective alkyne semi-hydrogenation as we embark on a journey through the first-row transition metals.

摘要

炔烃化学选择性和立体选择性半加氢生成烯烃是合成化学中的一项基本转化反应，使用贵重的4d或5d金属催化剂进行该反应已得到广泛认可。在人类对可持续性的不懈追求中，研究重点已大幅转向3d金属。鉴于其高丰度、易获取性以及较低的毒性，从经济和环境角度来看，它们无疑具有吸引力。在此，我们希望展示一些值得关注且具有开创性的例子，即在探索第一行过渡金属的过程中，使用3d金属催化剂进行非对映选择性炔烃半加氢反应。

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