Osovets S V, Azizova T V, Vasilenko E K
Radiats Biol Radioecol. 2017 Jan;57(1):12-17.
Individual doses from external γ-rays were estimated using biological dosimetry based on limited samplings (n₁= 15 and n₂ 12 individuals) which comprised the Mayak workers group with acute radiation sickness (ARS). The following primary data were used for calculation as initial parameters: estimated dose from ex- ternal γ-rays based on physical dosimetry methods - D (Gy); time before first vomiting - T (h); number of lymphocytes in peripheral blood on a second day after acute radiation exposure - L (10⁹/1); number of neutrophils in blood during first hours after accidental radiation exposure - N(10⁹/). A number of mathe- matical models used for dose estimation were verified: power-law dependence of the absorbed dose from ex- ternal γ-rays (D) on time before first vomiting (7), exponential dependence of D on the number of lympho- cytes in peripheral blood (L), dependence of D on the number of neutrophils in peripheral blood (N) and complex models forD association with Tand L parameters as well as-with Tand Nparameters. The biological dosimetry technique based on a complex approach was shown to provide the best agreement with physical dosimetry methods for individual assessment of doses from external γ-rays.
基于有限样本（n₁ = 15人，n₂ = 12人），利用生物剂量测定法估算了外部γ射线的个人剂量，这些样本来自患有急性放射病（ARS）的马亚克工人组。以下主要数据用作初始参数进行计算：基于物理剂量测定法的外部γ射线估计剂量 - D（Gy）；首次呕吐前的时间 - T（小时）；急性辐射暴露后第二天外周血中的淋巴细胞数量 - L（10⁹/升）；意外辐射暴露后最初几小时血液中的中性粒细胞数量 - N（10⁹/升）。对用于剂量估计的一些数学模型进行了验证：外部γ射线吸收剂量（D）与首次呕吐前时间（T）的幂律关系、D与外周血淋巴细胞数量（L）的指数关系、D与外周血中性粒细胞数量（N）的关系以及D与T和L参数以及与T和N参数关联的复杂模型。结果表明，基于综合方法的生物剂量测定技术在个人外部γ射线剂量评估方面与物理剂量测定方法最为吻合。
