Mahabadi Amir Abbas, Rischpler Christoph
Department of Cardiology and Vascular Medicine, West German Heart and Vascular Center, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
Department of Nuclear Medicine, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
J Thorac Dis. 2018 Dec;10(Suppl 35):S4351-S4366. doi: 10.21037/jtd.2018.10.92.
Cancer therapy may lead to cardiovascular complications and can promote each aspect of cardiac disease manifestation, such as vascular disease including coronary heart disease, myocardial diseases including heart failure, structural heart diseases including valvular heart diseases, and rhythm disorders. All potential complications of cancer therapy onto the cardiovascular system require imaging for diagnostic workup as well as monitoring of therapy. Transthoracic echocardiography (TTE) is the most frequently used tool for assessment of cardiac function during or after cancer therapy in daily clinical routine. With modern techniques like strain analysis, echocardiography allows to detect a variety of cardiac diseases as caused by cancer therapy even at subclinical stages. For further workup, specific imaging techniques including nuclear imaging are needed in a multimodality imaging approach to in detail characterize the underlying pathophysiology and to improve the management of the patients. Therefore, the field of imaging in cardio-oncology is rapidly growing. This review article will give an overview about existing literature regarding the role of imaging in the diagnostic evaluation and management of therapy in patient with prior or ongoing cancer therapy.
癌症治疗可能会导致心血管并发症,并可促使心脏病表现的各个方面出现,如包括冠心病在内的血管疾病、包括心力衰竭在内的心肌疾病、包括心脏瓣膜病在内的结构性心脏病以及心律失常。癌症治疗对心血管系统的所有潜在并发症都需要进行成像检查以进行诊断评估以及治疗监测。在日常临床实践中,经胸超声心动图(TTE)是癌症治疗期间或之后评估心脏功能最常用的工具。借助应变分析等现代技术,超声心动图甚至能够在亚临床阶段检测出由癌症治疗引起的多种心脏疾病。为了进一步检查,需要采用包括核成像在内的特定成像技术进行多模态成像,以详细表征潜在的病理生理学特征并改善患者的管理。因此,心脏肿瘤学的成像领域正在迅速发展。这篇综述文章将概述现有文献中关于成像在接受过或正在接受癌症治疗的患者的诊断评估和治疗管理中的作用。