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接受心脏手术的新生儿经胸心内和中心静脉置管的并发症

Complications of Transthoracic Intracardiac and Central Venous Lines in Neonates Undergoing Cardiac Surgery.

作者信息

Stein Mary Lyn, Quinonez Luis G, DiNardo James A, Brown Morgan L

机构信息

Department of Anesthesiology, Critical Care and Pain Medicine, Boston Children's Hospital, 300 Longwood Ave, Boston, MA, 02115, USA.

Division of Cardiovascular Surgery, Boston Children's Hospital, 300 Longwood Ave, Boston, MA, 02115, USA.

出版信息

Pediatr Cardiol. 2019 Apr;40(4):733-737. doi: 10.1007/s00246-019-02057-8. Epub 2019 Jan 30.

Abstract

Neonates undergoing congenital heart surgery require central venous access for diagnostic information and medication administration. There are multiple options for central access including peripherally inserted central catheters, umbilical, central venous, and transthoracic intracardiac lines. We retrospectively identified all patients younger than 30 days who underwent cardiac surgery in a 1-year period. Data were collected on demographic and medical characteristics, adverse events, pre-emptive transfusion of blood products prior to line removal, and transfusion of blood products following removal of transthoracic intracardiac lines and central venous lines. In our cohort of 124 neonates, 176 transthoracic intracardiac lines were placed in 113 patients. Eighty-two patients had pre-existing central venous access including 35 umbilical venous lines, 21 PICC lines, and 18 CVLs. Ninety-eight patients received a CVL in the operating room by anesthesia. Five patients were transfused to correct laboratory derangement prior to transthoracic intracardiac line removal. Transfusion of packed red blood cells (pRBC) occurred after transthoracic intracardiac line removal in 25 patients. Thrombus formation was present in one patient with a transthoracic intracardiac line and three patients with CVLs. One patient underwent surgical intervention for repositioning of a transthoracic intracardiac line. There were no cases of cardiac arrest, extracorporeal life support, or deaths attributable to lines. In this cohort, transthoracic intracardiac lines were generally safe. There were very few complications of thrombus, infection, or requirement for surgical intervention; however, transfusion of pRBCs following transthoracic intracardiac line removal occurred in 20% of patients.

摘要

接受先天性心脏手术的新生儿需要中心静脉通路来获取诊断信息和给药。中心静脉通路有多种选择,包括外周静脉穿刺中心静脉导管、脐静脉、中心静脉和经胸心内导管。我们回顾性确定了在1年期间接受心脏手术的所有30天以下的患者。收集了人口统计学和医学特征、不良事件、拔除导管前预防性输注血液制品以及拔除经胸心内导管和中心静脉导管后输注血液制品的数据。在我们的124例新生儿队列中,113例患者放置了176根经胸心内导管。82例患者已有中心静脉通路,包括35根脐静脉导管、21根外周静脉穿刺中心静脉导管和18根中心静脉导管。98例患者在手术室由麻醉医生置入中心静脉导管。5例患者在拔除经胸心内导管前因实验室指标异常接受输血治疗。25例患者在拔除经胸心内导管后输注了浓缩红细胞。1例经胸心内导管患者和3例中心静脉导管患者出现血栓形成。1例患者因经胸心内导管重新定位接受了手术干预。没有因导管导致心脏骤停、体外生命支持或死亡的病例。在这个队列中,经胸心内导管总体上是安全的。血栓、感染或手术干预的并发症很少;然而,20%的患者在拔除经胸心内导管后输注了浓缩红细胞。

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