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远程磁导航过程中的心电图获取。

Electrocardiogram Acquisition During Remote Magnetic Catheter Navigation.

机构信息

IADI, INSERM, U1254 and Université de Lorraine, Nancy, France.

Schiller Medical SAS, Wissembourg, France.

出版信息

Ann Biomed Eng. 2019 Apr;47(4):1141-1152. doi: 10.1007/s10439-019-02214-3. Epub 2019 Jan 30.

DOI:10.1007/s10439-019-02214-3
PMID:30701395
Abstract

Electrocardiogram (ECG) acquisition is required during catheter treatment of cardiac arrhythmias. The remote magnetic navigation technology allows the catheter to be moved automatically inside the heart chambers using large external magnets. Each change of position of the catheter requires fast motion of the magnets, therefore magnetic fluxes are created through the ECG cables, causing large distortions of the ECG signals. In this study a novel ECG sensor is proposed for reducing such distortions. The sensor uses short cables to connect the electrodes to the amplification and optical conversion circuit, using a technology similar to that used for magnetic resonance imaging. The proposed sensor was compared to the conventional 12-lead ECG device during various operation modes of the magnets. Quantitative morphological analysis of the different waves of the ECG was performed in two healthy subjects and on a conductivity phantom reproducing various cardiac pathologies. In healthy subjects the beat-to-beat correlation coefficients were improved with the proposed sensor for the PR interval (80-93% vs. 49-89%), QRS complex (93-96% vs. 74-94%), ST segment + T wave (95-98% vs. 67-99%), and whole PQRST wave (82-97% vs. 55-96%). Similar observations were made with the conductive gel in the whole PQRST wave in the pathological morphologies of the ECG for the VT (99% vs. 56-98%), AT (95% vs. 26-89%), ST (96-97% vs. 20-91%) and ST (96% vs. 28-90%). The new sensor might be used for better (uninterrupted) monitoring of the patient during catheter interventions using remote magnetic navigation. It has the potential to improve the robustness and/or duration of certain clinical procedures such as ventricular tachycardia ablation.

摘要

心电图(ECG)采集是心律失常导管治疗所必需的。远程磁导航技术允许使用大的外部磁铁自动移动心脏室内的导管。导管的每个位置变化都需要磁铁快速运动,因此通过 ECG 电缆产生磁通量,导致 ECG 信号的严重失真。在这项研究中,提出了一种新的 ECG 传感器来减少这种失真。该传感器使用短电缆将电极连接到放大和光转换电路,使用类似于磁共振成像(MRI)的技术。在磁铁的各种操作模式下,将提出的传感器与传统的 12 导联 ECG 设备进行了比较。在两名健康受试者和再现各种心脏病理的导电仿体上,对不同 ECG 波的定量形态学分析进行了研究。在健康受试者中,与传统的 12 导联 ECG 设备相比,PR 间隔(80-93%比 49-89%)、QRS 复合体(93-96%比 74-94%)、ST 段+T 波(95-98%比 67-99%)和整个 PQRST 波(82-97%比 55-96%)的逐搏相关系数得到了改善。在整个 PQRST 波的导电凝胶中,在 ECG 的病理性形态中也观察到了类似的现象,包括 VT(99%比 56-98%)、AT(95%比 26-89%)、ST(96-97%比 20-91%)和 ST(96%比 28-90%)。新型传感器可用于在使用远程磁导航的导管介入期间更好地(不间断地)监测患者。它有可能提高某些临床程序的鲁棒性和/或持续时间,例如室性心动过速消融。

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