Trobec Roman, Tomašić Ivan
Jozef Stefan Institute, Jamova cesta 39, 1000 Ljubljana, Slovenia.
IEEE Trans Inf Technol Biomed. 2011 Jul;15(4):615-21. doi: 10.1109/TITB.2011.2159236.
A new approach is proposed for synthesizing the standard 12-lead ECG from three differential leads formed by pairs of proximal electrodes on the body surface. The method is supported by a statistical analysis that gives the best personalized positions of electrodes. The measurements from multichannel ECGs were used to calculate the differential leads. Our algorithm searches for optimal differential leads and the corresponding personalized transformation matrix that is used to synthesize the standard 12-lead ECG. The algorithm has been evaluated on 99 multichannel ECGs measured on 30 healthy subjects and 35 patients scheduled for elective cardiac surgery. It is shown that the algorithm significantly outperforms the synthesis based on the EASI lead system with medians of correlation coefficients greater than 0.954 for all 12 standard leads. To determine the optimal number of differential leads, the syntheses for two, three, and four differential leads were calculated. The analysis shows that 3 is the optimal number of differential leads for practical applications. Because of the proximity of the differential electrodes, the proposed approach offers an opportunity for the synthesis of a standard 12-lead ECG with wireless electrodes.
本文提出了一种新方法，可根据体表近端电极对形成的三个差分导联合成标准12导联心电图。该方法得到了一项统计分析的支持，该分析给出了电极的最佳个性化位置。利用多通道心电图的测量值来计算差分导联。我们的算法搜索最佳差分导联和相应的个性化变换矩阵，用于合成标准12导联心电图。该算法已在30名健康受试者和35名计划进行择期心脏手术的患者身上测量的99份多通道心电图上进行了评估。结果表明，该算法明显优于基于EASI导联系统的合成方法，所有12个标准导联的相关系数中位数均大于0.954。为了确定差分导联的最佳数量，计算了两个、三个和四个差分导联的合成结果。分析表明，3是实际应用中差分导联的最佳数量。由于差分电极距离较近，所提出的方法为使用无线电极合成标准12导联心电图提供了机会。
