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远程医疗创新在 HIV 暴露前预防(PrEP)中的应用综述

A Review of Telehealth Innovations for HIV Pre-Exposure Prophylaxis (PrEP).

机构信息

University of Washington, 325 9th Ave, Harborview 2W Clinic, Seattle, WA, 98104, USA.

Division of Allergy and Infectious Diseases, University of Washington, Seattle, WA, USA.

出版信息

Curr HIV/AIDS Rep. 2019 Feb;16(1):113-119. doi: 10.1007/s11904-019-00430-z.

DOI:10.1007/s11904-019-00430-z
PMID:30701404
Abstract

PURPOSE OF REVIEW

This review summarizes novel interventions that employ technology to improve HIV pre-exposure prophylaxis (PrEP) availability, uptake, and adherence.

RECENT FINDINGS

Several notable technology-based programs are increasing access to PrEP in unique ways. We identified multiple models for using telehealth to bolster PrEP dissemination and adherence, such as mobile applications that offer PrEP prescribing without an in-person visit, longitudinal distance telementoring for community provider PrEP education and clinical guidance, and electronic consults for PrEP specialist support in the primary care setting. Outcomes data for all of these modalities are limited but show promise. Technology-based interventions can address gaps in the PrEP care continuum. Future research should assess and compare outcomes, scalability, cost-effectiveness, and sustainability. Costs associated with the creation of new technological tools slow innovation and the field would benefit from a platform for technology sharing.

摘要

目的综述

本综述总结了利用技术提高 HIV 暴露前预防 (PrEP) 的可及性、使用率和依从性的新干预措施。

最新发现

一些值得注意的基于技术的项目正在以独特的方式增加 PrEP 的可及性。我们确定了多种利用远程医疗来加强 PrEP 传播和依从性的模式,例如提供无需面访即可开处 PrEP 的移动应用程序、为社区提供者提供 PrEP 教育和临床指导的纵向远程指导、以及在初级保健环境中为 PrEP 专家支持提供电子咨询。所有这些模式的结果数据都很有限,但有希望。基于技术的干预措施可以解决 PrEP 护理连续体中的差距。未来的研究应该评估和比较结果、可扩展性、成本效益和可持续性。创建新的技术工具的相关成本阻碍了创新,该领域将受益于一个技术共享平台。

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本文引用的文献

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Developing and Assessing the Feasibility of a Home-based Preexposure Prophylaxis Monitoring and Support Program.开发并评估基于家庭的暴露前预防监测和支持方案的可行性。
Clin Infect Dis. 2019 Jan 18;68(3):501-504. doi: 10.1093/cid/ciy529.
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Knowledge, Practices, and Barriers to HIV Preexposure Prophylaxis Prescribing Among Washington State Medical Providers.华盛顿州医疗服务提供者对 HIV 暴露前预防用药的认知、实践和障碍。
Sex Transm Dis. 2018 Jul;45(7):452-458. doi: 10.1097/OLQ.0000000000000781.
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Barriers to Access and Adoption of Pre-Exposure Prophylaxis for the Prevention of HIV Among Men Who Have Sex With Men (MSM) in a Relatively Rural State.
Multilevel Intervention to Support Tailored and Responsive HIV Pre-Exposure Prophylaxis Care in Rural North Carolina: Protocol for a Randomized Controlled Trial.
北卡罗来纳州农村地区支持定制化和响应式HIV暴露前预防护理的多层次干预:一项随机对照试验方案
JMIR Res Protoc. 2025 Mar 21;14:e68085. doi: 10.2196/68085.
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Rationale and design of a randomized clinical trial of integrated eHealth for PrEP and medications for opioid use disorders for women in the criminal legal system. The Athena study.针对刑事司法系统中女性的暴露前预防(PrEP)和阿片类药物使用障碍药物综合电子健康随机临床试验的基本原理与设计。雅典娜研究。
Addict Sci Clin Pract. 2025 Jan 17;20(1):4. doi: 10.1186/s13722-024-00534-x.
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Transforming HIV prevention: the promise of long-acting preexposure prophylaxis in high HIV burden settings.转变HIV预防方式:在高HIV负担地区长效暴露前预防的前景
Curr Opin HIV AIDS. 2025 Jan 1;20(1):32-38. doi: 10.1097/COH.0000000000000895. Epub 2024 Nov 4.
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Preferences for pre-exposure prophylaxis delivery via online pharmacy among potential users in Kenya: a discrete choice experiment.肯尼亚潜在用户对通过在线药店提供暴露前预防措施的偏好:一项离散选择实验。
J Int AIDS Soc. 2024 Oct;27(10):e26356. doi: 10.1002/jia2.26356.
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Exploring adolescent girls and young women's PrEP-user profiles: qualitative insights into differentiated PrEP delivery platform selection and engagement in Cape Town, South Africa.探索少女和年轻女性的 PrEP 用户特征:南非开普敦对差异化 PrEP 提供平台选择和参与的定性洞察。
J Int AIDS Soc. 2024 May;27(5):e26254. doi: 10.1002/jia2.26254.
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AIDS Educ Prev. 2017 Aug;29(4):315-329. doi: 10.1521/aeap.2017.29.4.315.
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LGBT Health. 2017 Aug;4(4):310-314. doi: 10.1089/lgbt.2016.0068. Epub 2017 May 17.
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PrEP Awareness, Familiarity, Comfort, and Prescribing Experience among US Primary Care Providers and HIV Specialists.美国初级保健提供者和HIV专家对暴露前预防(PrEP)的认知、熟悉程度、接受度及处方经验
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Outcomes of treatment for hepatitis C virus infection by primary care providers.基层医疗服务提供者治疗丙型肝炎病毒感染的结果。
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