Tanashyan M M, Kuznetsova P I, Raskurazhev A A, Subortseva I N, Melikyan A L
Research Center of Neurology, Moscow, Russia.
National Research Center of Hematology, Moscow, Russia.
Ter Arkh. 2018 Aug 17;90(7):102-104. doi: 10.26442/terarkh2018907102-104.
This article describes several clinical cases of acute ischemic stroke among patients suffering from essential thrombocytemia. Ambiguity of etiological factors of stroke is demonstrated among patients with this pathology. Thrombocytosis and high allele load in the Jak2 gene play an important role (even with normal platelet count) in progression of cerebrovascular disease. Also the question of effectiveness of preventive and etiological therapy is considered.
本文描述了原发性血小板增多症患者中几例急性缺血性中风的临床病例。在患有这种病症的患者中，中风病因因素存在不确定性。血小板增多症以及Jak2基因中的高等位基因负荷（即使血小板计数正常）在脑血管疾病进展中起重要作用。此外，还探讨了预防性和病因性治疗的有效性问题。
