• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

左冠状动脉主干完全血栓形成的左心发育不良综合征婴儿经冠状动脉内重组组织型纤溶酶原激活剂溶栓治疗

Intracoronary recombinant tissue plasminogen activator in an infant with hypoplastic left heart syndrome and complete left main coronary artery thrombosis.

机构信息

Congenital Heart Center, Spectrum Health Helen DeVos Children's Hospital, Grand Rapids, Michigan.

West Michigan Anesthesia, PC, Grand Rapids, Michigan.

出版信息

Catheter Cardiovasc Interv. 2019 Jun 1;93(7):E381-E384. doi: 10.1002/ccd.28092. Epub 2019 Jan 31.

DOI:10.1002/ccd.28092
PMID:30702202
Abstract

An infant with hypoplastic left heart syndrome (HLHS) presented with complete heart block and severe myocardial dysfunction requiring ECMO support due to complete left main coronary artery (LMCA) thrombosis. Current guidelines for managing coronary artery thrombosis in infants with single ventricle physiology are inadequate. We describe successful LMCA and branch recanalization via intra coronary infusion of recombinant tissue plasminogen activator and discuss management of acute coronary thrombosis in children with single ventricle physiology.

摘要

一名患有左心发育不全综合征(HLHS)的婴儿因完全性左主干冠状动脉(LMCA)血栓形成导致完全性心脏传导阻滞和严重心肌功能障碍,需要 ECMO 支持。目前针对单心室生理患儿冠状动脉血栓形成的治疗指南并不完善。我们通过冠状动脉内输注重组组织型纤溶酶原激活剂成功地进行了 LMCA 和分支再通,并讨论了单心室生理患儿急性冠状动脉血栓形成的治疗方法。

相似文献

1
Intracoronary recombinant tissue plasminogen activator in an infant with hypoplastic left heart syndrome and complete left main coronary artery thrombosis.左冠状动脉主干完全血栓形成的左心发育不良综合征婴儿经冠状动脉内重组组织型纤溶酶原激活剂溶栓治疗
Catheter Cardiovasc Interv. 2019 Jun 1;93(7):E381-E384. doi: 10.1002/ccd.28092. Epub 2019 Jan 31.
2
Successful management of neonatal myocardial infarction with ECMO and intracoronary r-tPA lysis.采用体外膜肺氧合(ECMO)和冠状动脉内重组组织型纤溶酶原激活剂(r-tPA)溶栓成功治疗新生儿心肌梗死。
Congenit Heart Dis. 2014 Sep-Oct;9(5):E169-74. doi: 10.1111/chd.12117. Epub 2013 Jul 1.
3
Regional thrombolysis with tenecteplase during extracorporeal membrane oxygenation: a new approach for left ventricular thrombosis.体外膜肺氧合期间使用替奈普酶进行局部溶栓:治疗左心室血栓的新方法。
J Card Surg. 2015 Jun;30(6):541-3. doi: 10.1111/jocs.12556. Epub 2015 May 5.
4
Coronary thrombolysis with recombinant tissue plasminogen activator. Intracoronary vs intravenous administration.重组组织型纤溶酶原激活剂冠状动脉溶栓治疗。冠状动脉内给药与静脉内给药对比。
Chest. 1991 Jul;100(1):201-6. doi: 10.1378/chest.100.1.201.
5
The use of recombinant tissue-type plasminogen activator in a newborn with an intracardiac thrombus developed during extracorporeal membrane oxygenation.在体外膜氧合过程中发生心内血栓的新生儿中使用重组组织型纤溶酶原激活物。
J Pediatr Surg. 2011 Oct;46(10):2021-4. doi: 10.1016/j.jpedsurg.2011.06.039.
6
Recombinant tissue plasminogen activator (rt-PA): is it the thrombolytic agent of choice for an evolving acute myocardial infarction?重组组织型纤溶酶原激活剂(rt-PA):它是正在进展的急性心肌梗死的首选溶栓剂吗?
Am J Cardiol. 1987 Apr 15;59(9):984-9. doi: 10.1016/0002-9149(87)91139-8.
7
Primary percutaneous coronary intervention of an unprotected left main using mini-crush drug-eluting stents facilitated by intracoronary reteplase.经冠状动脉内瑞替普酶辅助的微 Crushing 药物洗脱支架行非保护左主干的直接经皮冠状动脉介入治疗。
Catheter Cardiovasc Interv. 2011 Mar 1;77(4):515-21. doi: 10.1002/ccd.22815. Epub 2011 Jan 4.
8
A new drug delivery system for intravenous coronary thrombolysis with thrombus targeting and stealth activity recoverable by ultrasound.一种新型的静脉冠状动脉溶栓药物输送系统,具有血栓靶向和超声可恢复的隐身活性。
J Am Coll Cardiol. 2012 Dec 18;60(24):2550-7. doi: 10.1016/j.jacc.2012.08.1008. Epub 2012 Nov 14.
9
Use of tissue plasminogen activator to treat intracardiac thrombosis in extremely low-birth-weight infants.应用组织型纤溶酶原激活物治疗极低出生体重儿心内血栓。
Pediatr Crit Care Med. 2011 Nov;12(6):e407-9. doi: 10.1097/PCC.0b013e3181fe449f.
10
Coronary thrombolysis. Comparative effects of intracoronary administration of recombinant tissue plasminogen activator and urokinase.冠状动脉溶栓。冠状动脉内注射重组组织型纤溶酶原激活剂与尿激酶的比较效果。
Chest. 1992 Jun;101(6):1684-90. doi: 10.1378/chest.101.6.1684.

引用本文的文献

1
The probable role of tissue plasminogen activator/neuroserpin axis in Alzheimer's disease: a new perspective.组织型纤溶酶原激活物/神经丝氨酸蛋白酶抑制剂轴在阿尔茨海默病中的可能作用:新视角。
Acta Neurol Belg. 2024 Apr;124(2):377-388. doi: 10.1007/s13760-023-02403-x. Epub 2023 Nov 2.
2
Native Aortic Root Thrombus in 3-Year-Old Fontan Patient with Hypoplastic Left Heart Syndrome: Presentation and Echocardiographic Findings of This Life-Threatening Complication.患有左心发育不全综合征的3岁Fontan手术患者的原发性主动脉根部血栓:这种危及生命并发症的表现及超声心动图检查结果
CASE (Phila). 2021 Aug 12;5(5):276-279. doi: 10.1016/j.case.2021.07.007. eCollection 2021 Oct.