Suppr超能文献

基于深度神经网络的高清MRI直肠淋巴结辅助诊断系统

[High definition MRI rectal lymph node aided diagnostic system based on deep neural network].

作者信息

Zhou Y P, Li S, Zhang X X, Zhang Z D, Gao Y X, Ding L, Lu Y

机构信息

Department of Gastrointestinal Surgery, Affiliated Hospital of Qingdao University, Qingdao 266000, China.

Beihang University Qingdao Research Institute, Qingdao 266000, China.

出版信息

Zhonghua Wai Ke Za Zhi. 2019 Feb 1;57(2):108-113. doi: 10.3760/cma.j.issn.0529-5815.2019.02.007.

Abstract

To investigate the clinical significance of high definition (HD) MRI rectal lymph node aided diagnostic system based on deep neural network. The research selected 301 patients with rectal cancer who underwent pelvic HD MRI and reported pelvic lymph node metastasis from July 2016 to December 2017 in Affiliated Hospital of Qingdao University. According to the chronological order, the first 201 cases were used as learning group. The remaining 100 cases were used as verification group. There were 149 males (74.1%) and 52 females in the study group, with an average age of 58.8 years. There were 76 males (76.0%) and 24 females in the validation group, with an average age of 60.2 years. Firstly, Using deep learning technique, researchers trained the 12 060 HD MRI lymph nodes images data of learning group with convolution neural network to simulate the judgment process of radiologists, and established an artificial intelligence automatic recognition system for metastatic lymph nodes of rectal cancer. Then, 6 030 images of the validation group were clinically validated. Artificial intelligence and radiologists simultaneously diagnosed all cases of HD MRI images and made the diagnosis results of metastatic lymph node. Receiver operating characteristic (ROC) curve and area under curve (AUC) were used to compare the diagnostic level of them. After continuous iteration training of the learning group data, the loss function value of artificial intelligence decreased continuously, and the diagnostic error decreased continuously. Among the 6 030 images of verification group, 912 images were considered to exist metastatic lymph nodes in radiologists' diagnosis and 987 in artificial intelligence diagnosis. There were 772 images having identical diagnostic results of lymph node location and number of metastases with the two methods. Compared with manual diagnosis, the AUC of the intelligent platform was 0.886 2, the diagnostic time of a single case was 10 s, but the average diagnostic time of doctors was 600 s. The HD MRI lymph node automatic recognition system based on deep neural network has high accuracy and high efficiency, and has the clinical significance of auxiliary diagnosis.

摘要

探讨基于深度神经网络的高清(HD)MRI直肠淋巴结辅助诊断系统的临床意义。本研究选取2016年7月至2017年12月在青岛大学附属医院接受盆腔HD MRI检查并报告盆腔淋巴结转移情况的301例直肠癌患者。按时间顺序,将前201例作为学习组,其余100例作为验证组。研究组男性149例(74.1%),女性52例,平均年龄58.8岁。验证组男性76例(76.0%),女性24例,平均年龄60.2岁。首先,研究人员利用深度学习技术,用卷积神经网络对学习组的12060例HD MRI淋巴结图像数据进行训练,模拟放射科医生的判断过程,建立了直肠癌转移淋巴结人工智能自动识别系统。然后,对验证组的6030例图像进行临床验证。人工智能和放射科医生同时对所有HD MRI图像病例进行诊断,并得出转移淋巴结的诊断结果。采用受试者操作特征(ROC)曲线和曲线下面积(AUC)比较二者的诊断水平。经过对学习组数据的持续迭代训练,人工智能的损失函数值不断下降,诊断误差不断降低。在验证组的6030例图像中,放射科医生诊断认为存在转移淋巴结的有912例,人工智能诊断为987例。两种方法对淋巴结位置和转移数量诊断结果相同的有772例。与人工诊断相比,智能平台的AUC为0.886 2,单例诊断时间为10秒,而医生的平均诊断时间为600秒。基于深度神经网络的HD MRI淋巴结自动识别系统具有较高的准确性和效率,具有辅助诊断的临床意义。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验