多发性硬化症与中枢神经系统自身免疫性神经病
Multiple Sclerosis and Autoimmune Neurology of the Central Nervous System.
机构信息
Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA; Department of Neurology, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA.
Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA.
出版信息
Med Clin North Am. 2019 Mar;103(2):325-336. doi: 10.1016/j.mcna.2018.10.004. Epub 2018 Dec 3.
Autoimmune disorders of the central nervous system are common and often affect people in the most productive years of their lives. Among primary autoimmune diseases of the central nervous system, multiple sclerosis is most prevalent in the United States. Many other autoantibody-mediated neurologic syndromes have been identified within the past 2 to 3 decades, including neuromyelitis optica and anti-N-methyl-D aspartate receptor encephalitis. Finally, the central nervous system can also be affected by systemic autoimmune diseases such as sarcoidosis. Many of these diseases are treatable when detected early.
中枢神经系统自身免疫性疾病很常见，且常发生于人们生产力最高的年龄段。在原发性中枢神经系统自身免疫性疾病中，多发性硬化在美国最为常见。在过去 2 至 3 十年间，还发现了许多其他的抗体介导的神经综合征，包括视神经脊髓炎和抗 N-甲基-D-天冬氨酸受体脑炎。最后，中枢神经系统也可能受到结节病等系统性自身免疫性疾病的影响。这些疾病中的许多在早期发现时是可以治疗的。
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