Department of Pediatrics, University of Minnesota, 717 Delaware St SE, Minneapolis, MN, 55414, USA.
Institute on Community Integration, University of Minnesota, 150 Pillsbury Dr SE, Minneapolis, MN, 55455, USA.
J Autism Dev Disord. 2019 Jun;49(6):2291-2303. doi: 10.1007/s10803-019-03903-7.
Individuals with autism spectrum disorder (ASD) have higher rates of co-occurring diagnoses and use of psychotropic medication prescriptions than people with other developmental disabilities. Few studies have examined these trends in samples of people with intellectual and developmental disabilities (IDD) with and without ASD. Using a random sample of 11,947 adult IDD service users from 25 states, co-occurring diagnoses and psychotropic medication use were compared for those with and without ASD. Regardless of diagnosis, individuals with ASD had higher percentages of psychotropic medication use. Controlling for co-occurring condition, age, gender, and ID level, a diagnosis of ASD predicted number of medications used. Further research is needed to understand why individuals with ASD are prescribed more medication, more often, than similarly functioning groups of individuals without ASD.
自闭症谱系障碍（ASD）患者比其他发育障碍患者更常共患其他诊断，并使用精神药物处方。很少有研究在有和没有 ASD 的智力和发育障碍（IDD）患者样本中检查这些趋势。使用来自 25 个州的 11947 名成年 IDD 服务使用者的随机样本，比较了有和没有 ASD 的患者的共患诊断和精神药物使用情况。无论诊断如何，患有 ASD 的个体使用精神药物的比例更高。在控制共患疾病、年龄、性别和 ID 水平后，ASD 诊断预测了使用的药物数量。需要进一步研究以了解为什么 ASD 患者比没有 ASD 的同样功能组的个体更常、更频繁地开出更多药物。
