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简短报告:成年自闭症谱系障碍患者自我报告的药物使用情况:2012年至2022年美国诊所样本

Brief Report: Self-Reported Medication Use in Individuals Diagnosed with Autism Spectrum Disorder in Adulthood: A U.S. Clinic Sample from 2012 to 2022.

作者信息

Izuno-Garcia A K, Vanderburg J L, Pagán A F, Loveland K A

机构信息

Louis A. Faillace, MD, Department of Psychiatry and Behavioral Sciences, McGovern Medical School, University of Texas Health Science Center, Houston, TX, USA.

出版信息

J Autism Dev Disord. 2024 May 23. doi: 10.1007/s10803-024-06397-0.

Abstract

PURPOSE

As the understanding of autism spectrum disorder (ASD) across the lifespan has increased, so has the number of individuals being identified with ASD for the first time in adulthood. Understanding co-occurring psychiatric conditions in this subset of the ASD population is a growing focus of research; however, little is known about the rate at which psychiatric medications are prescribed to adults with a first-time diagnosis of ASD. The purpose of this study was to examine self-reported medication use in persons diagnosed with ASD in adulthood in a clinic sample (2012-2022) in the United States.

METHODS

The present study was a retrospective record review. Participants (n = 281) were drawn from an outpatient clinic specializing in the diagnosis of ASD in adults. Participants self-reported previous and current psychiatric medication prescription using a medication checklist.

RESULTS

Approximately 50% of participants self-reported being prescribed at least one psychiatric medication at the time of their initial evaluation appointment. The most commonly prescribed psychiatric medications were antidepressants (23.8%), followed by stimulants (16.7%).

CONCLUSION

Similar to individuals diagnosed with ASD in childhood, those identified with ASD for the first time in adulthood are prescribed psychiatric medication at a much higher rate than their same-age non-autistic peers. These results can inform future research and practice for improving outcomes for autistic adults, particularly those who were undiagnosed for much of their lives.

摘要

目的

随着对自闭症谱系障碍(ASD)全生命周期的认识不断提高,成年后首次被诊断为ASD的人数也在增加。了解ASD人群中这一亚组共病的精神疾病状况日益成为研究重点;然而,对于首次诊断为ASD的成年人开具精神科药物的比例知之甚少。本研究的目的是在美国一个临床样本(2012 - 2022年)中,调查成年后被诊断为ASD的人群自我报告的用药情况。

方法

本研究为回顾性病历审查。参与者(n = 281)来自一家专门诊断成人ASD的门诊诊所。参与者使用药物清单自我报告既往和当前的精神科药物处方情况。

结果

约50%的参与者在初次评估就诊时自我报告至少开具了一种精神科药物。最常开具的精神科药物是抗抑郁药(23.8%),其次是兴奋剂(16.7%)。

结论

与童年时期被诊断为ASD的个体相似,成年后首次被诊断为ASD的个体开具精神科药物的比例远高于同龄非自闭症同龄人。这些结果可为未来改善自闭症成年人结局的研究和实践提供参考,尤其是那些一生中大部分时间未被诊断的人。

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