Izuno-Garcia A K, Vanderburg J L, Pagán A F, Loveland K A
Louis A. Faillace, MD, Department of Psychiatry and Behavioral Sciences, McGovern Medical School, University of Texas Health Science Center, Houston, TX, USA.
J Autism Dev Disord. 2024 May 23. doi: 10.1007/s10803-024-06397-0.
As the understanding of autism spectrum disorder (ASD) across the lifespan has increased, so has the number of individuals being identified with ASD for the first time in adulthood. Understanding co-occurring psychiatric conditions in this subset of the ASD population is a growing focus of research; however, little is known about the rate at which psychiatric medications are prescribed to adults with a first-time diagnosis of ASD. The purpose of this study was to examine self-reported medication use in persons diagnosed with ASD in adulthood in a clinic sample (2012-2022) in the United States.
The present study was a retrospective record review. Participants (n = 281) were drawn from an outpatient clinic specializing in the diagnosis of ASD in adults. Participants self-reported previous and current psychiatric medication prescription using a medication checklist.
Approximately 50% of participants self-reported being prescribed at least one psychiatric medication at the time of their initial evaluation appointment. The most commonly prescribed psychiatric medications were antidepressants (23.8%), followed by stimulants (16.7%).
Similar to individuals diagnosed with ASD in childhood, those identified with ASD for the first time in adulthood are prescribed psychiatric medication at a much higher rate than their same-age non-autistic peers. These results can inform future research and practice for improving outcomes for autistic adults, particularly those who were undiagnosed for much of their lives.
随着对自闭症谱系障碍(ASD)全生命周期的认识不断提高,成年后首次被诊断为ASD的人数也在增加。了解ASD人群中这一亚组共病的精神疾病状况日益成为研究重点;然而,对于首次诊断为ASD的成年人开具精神科药物的比例知之甚少。本研究的目的是在美国一个临床样本(2012 - 2022年)中,调查成年后被诊断为ASD的人群自我报告的用药情况。
本研究为回顾性病历审查。参与者(n = 281)来自一家专门诊断成人ASD的门诊诊所。参与者使用药物清单自我报告既往和当前的精神科药物处方情况。
约50%的参与者在初次评估就诊时自我报告至少开具了一种精神科药物。最常开具的精神科药物是抗抑郁药(23.8%),其次是兴奋剂(16.7%)。
与童年时期被诊断为ASD的个体相似,成年后首次被诊断为ASD的个体开具精神科药物的比例远高于同龄非自闭症同龄人。这些结果可为未来改善自闭症成年人结局的研究和实践提供参考,尤其是那些一生中大部分时间未被诊断的人。