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颞下颌关节骨关节炎和水平髁突角增大:一项纵向研究。

Osteoarthritis of the temporomandibular joint and increase of the horizontal condylar angle: a longitudinal study.

机构信息

Assistant Professor, Assistant Program Director, Oral and Maxillofacial Radiology Residency Program, Department of Oral Medicine, University of Washington, Seattle, WA, USA.

Dental Student, Department of Oral Medicine, University of Washington, Seattle, WA, USA.

出版信息

Oral Surg Oral Med Oral Pathol Oral Radiol. 2019 Apr;127(4):339-350. doi: 10.1016/j.oooo.2018.12.014. Epub 2018 Dec 31.

Abstract

OBJECTIVE

Our previous study of patients with unilateral temporomandibular joint (TMJ) osteoarthritis (OA) showed that the affected joints had greater horizontal condylar angle (HCA) compared with the contralateral unaffected joints. However, it was unclear whether the HCA changes preceded or were the result of OA changes. The aim of this longitudinal study was to investigate the relationship between HCA and OA progression.

STUDY DESIGN

In total, 127 patients (with or without TMJ disorders) completed baseline and follow-up examinations (average time to follow-up 7.9 years). Generalized estimating equation models were used to account for correlation of observations within the same patients.

RESULTS

(1) HCA was greater in OA-affected joints than in unaffected joints (P = .04). (2) Increased HCA at follow-up was associated with change in joint status from no OA to OA. (P = .001). (3) Baseline HCA value alone did not predict future OA diagnosis. (4) All OA changes in fossa/articular eminence morphology, and some combinations of condylar changes, were associated with a greater HCA. (5) OA diagnosis was associated with pain during maximum opening (P = .005) and pain history (P = .002). (6) Aging alone was not correlated with increased HCA.

CONCLUSIONS

Clinical progression of OA preceded increases in HCA. HCA alone did not predict OA development.

摘要

目的

我们之前对单侧颞下颌关节(TMJ)骨关节炎(OA)患者的研究表明,患病关节的水平髁突角(HCA)大于对侧未受影响的关节。然而,尚不清楚 HCA 的变化是先于 OA 变化发生,还是由 OA 变化引起的。本纵向研究旨在探讨 HCA 与 OA 进展之间的关系。

研究设计

共有 127 名患者(有或没有 TMJ 紊乱)完成了基线和随访检查(平均随访时间为 7.9 年)。使用广义估计方程模型来解释同一患者内观察结果的相关性。

结果

(1)OA 受累关节的 HCA 大于未受累关节(P=0.04)。(2)随访时 HCA 的增加与关节状态从无 OA 变为 OA 有关(P=0.001)。(3)基线 HCA 值本身不能预测未来的 OA 诊断。(4)窝/关节突形态的所有 OA 变化以及髁突变化的某些组合,均与更大的 HCA 相关。(5)OA 诊断与最大开口时的疼痛(P=0.005)和疼痛史(P=0.002)有关。(6)单纯衰老与 HCA 的增加无关。

结论

OA 的临床进展先于 HCA 的增加。HCA 本身不能预测 OA 的发展。

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