Okamura Keisuke, Okuda Tetsu, Fukuda Yusuke, Takamiya Yosuke, Shirai Kazuyuki, Miyajima Shigerou, Ishii Tatsu, Urata Hidenori
Department of Cardiovascular Diseases, Fukuoka University Chikushi Hospital, Chikushino, Fukuoka, Japan.
Fukuda Clinic, Fukuoka, Japan.
Am J Case Rep. 2019 Feb 2;20:139-145. doi: 10.12659/AJCR.913172.
BACKGROUND Before partial adrenalectomy for primary aldosteronism due to a primary adrenal adenoma, the aldosterone-producing tumor can be localized by segmental adrenal vein sampling (S-AVS). Cardiologists, who regularly perform percutaneous coronary intervention (PCI), or coronary angioplasty with stent, may not be familiar with the technique of S-AVS. A case of the use of S-AVS is reported in a patient who presented with primary aldosteronism and a right adrenal adenoma. CASE REPORT A 44-year-old man with a history of hypertension presented with a man in the posterior part of the right adrenal gland. He had hypokalemia, and a high plasma aldosterone concentration/plasma renin activity ratio. A captopril stress test confirmed the diagnosis of primary aldosteronism. Pre-operative S-AVS was performed using a microwire and microcatheter, which were advanced into the segmental adrenal vein using a 6.5 French guiding catheter and a Y-shaped connector, under biplane cine angiography guidance. S-AVS showed a high plasma aldosterone concentration in the right superior tributary adrenal vein draining the adrenal mass. Right partial adrenalectomy was performed. Postoperatively, the patient's blood pressure and plasma aldosterone levels normalized. CONCLUSIONS S-AVS can be performed relatively easily before partial adrenalectomy using a catheter system with biplane cine angiography, which is a technique that is familiar to cardiologists.
在因原发性肾上腺腺瘤进行原发性醛固酮增多症的部分肾上腺切除术之前,可通过肾上腺静脉分段采血(S-AVS)对产生醛固酮的肿瘤进行定位。经常进行经皮冠状动脉介入治疗(PCI)或冠状动脉支架血管成形术的心脏病专家可能不熟悉S-AVS技术。本文报告了一例原发性醛固酮增多症合并右肾上腺腺瘤患者使用S-AVS的病例。病例报告:一名44岁有高血压病史的男性,右侧肾上腺后部发现一个肿块。他有低钾血症,血浆醛固酮浓度/血浆肾素活性比值升高。卡托普利激发试验确诊为原发性醛固酮增多症。术前在双平面血管造影引导下,使用微导丝和微导管,通过6.5法国引导导管和Y形连接器将其推进到肾上腺静脉段进行S-AVS。S-AVS显示引流肾上腺肿块的右肾上腺上支静脉血浆醛固酮浓度高。进行了右肾上腺部分切除术。术后,患者血压和血浆醛固酮水平恢复正常。结论:使用双平面血管造影导管系统在部分肾上腺切除术之前相对容易进行S-AVS,这是一种心脏病专家熟悉的技术。