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炔诺孕酮和氯地孕酮对人输卵管自发运动的影响。

The effect of norgestrel and clogestone on the spontaneous motility of the human fallopian tube.

作者信息

Elder M G, Myatt L, Chaudhuri G

出版信息

Int J Fertil. 1978;23(1):61-4.

PMID:30711
Abstract

Spontaneous isometric contractions in vitro of both isthmic and ampullary parts of the human fallopian tube were studied. The tubes were obtained during the early luteal phase of the menstrual cycle from patients undergoing abdominal hysterectomy and who had ingested clogestone acetate or norgestrel, either 1 or 12 hours prior to the experiment. A dose of 150 microgram dl-norgestrel given orally 12 hours preoperatively caused a significant increase in the frequency of spontaneous isometric contractions together with a significant reduction in the area under the curve for each contraction. The possible effect of this altered pattern of motility is discussed.

摘要

对人体输卵管峡部和壶腹部的体外自发性等长收缩进行了研究。这些输卵管是在月经周期的黄体早期从接受腹部子宫切除术的患者身上获取的,这些患者在实验前1或12小时摄入了醋酸氯地孕酮或炔诺孕酮。术前12小时口服150微克消旋炔诺孕酮可使自发性等长收缩频率显著增加,同时每次收缩的曲线下面积显著减小。讨论了这种运动模式改变的可能影响。

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