Togashi M, Arakawa M, Tsubo S, Sakashita S, Maru A, Koyanagi T, Nakanishi S, Kakizaki H, Minami S, Kanagawa K
Department of Urology, Hokkaido University of Medicine.
Hinyokika Kiyo. 1988 Dec;34(12):2233-6.
Enoxacin (ENX) was administered to 69 patients with complicated urinary tract infections (UTI). Clinical efficacy and safety were evaluated by the criteria proposed by the UTI Committee, Japan. The overall clinical efficacy was excellent in 60.9%, moderate in 10.1% and poor in 29% of the patients. Of the 76 strains isolated from the patients 61 strains (80.3%) were eradicated. Subjective side effect was observed in one patient who complained of slight nausea. No drug-related aggravation in the laboratory test was observed. These results showed that ENX was effective and safety for the treatment of complicated urinary tract infection.
对69例复杂性尿路感染(UTI)患者给予依诺沙星(ENX)治疗。根据日本UTI委员会提出的标准评估临床疗效和安全性。患者的总体临床疗效为:60.9%极佳,10.1%中等,29%较差。从患者中分离出的76株菌株中,61株(80.3%)被根除。有1例患者主诉轻微恶心,观察到主观副作用。未观察到实验室检查中与药物相关的恶化情况。这些结果表明,依诺沙星治疗复杂性尿路感染有效且安全。