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依诺沙星治疗复杂性尿路感染的长期疗效及临床评估

[Long-term treatment and clinical evaluation of enoxacin in complicated urinary tract infections].

作者信息

Washida H, Sakagami H, Iwase Y, Sasaki S

机构信息

Department of Urology, Anjo Kosei Hospital.

出版信息

Hinyokika Kiyo. 1987 Sep;33(9):1508-12.

PMID:3481218
Abstract

Enoxacin (ENX) was used in the treatment of 16 patients with complicated urinary tract infections. ENX was orally administered 600 mg three times a day for 14--32 days. Clinical results evaluated according to the criteria of UTI committee were excellent in 6 cases, moderate in 3 cases and poor in 6 cases. The overall efficacy rate was 60.0%. Two moderate cases at 5 days showed excellent results at 14 days. Twelve out of 18 bacteriological strains were eradicated, with the elimination rate of 66.7%. As side effects, slight constipation occurred in one patient, and he was treated with purgatives. Photoallergic eruptions occurred in one of the 16 patients. He was treated with an antihistaminic agent and soon recovered.

摘要

依诺沙星(ENX)用于治疗16例复杂性尿路感染患者。依诺沙星口服给药,剂量为600毫克,每日3次,疗程为14 - 32天。根据泌尿道感染委员会的标准评估临床结果,6例为优,3例为中,6例为差。总有效率为60.0%。2例中度患者在第5天时情况,在第14天时显示为优。18株细菌菌株中有12株被根除,清除率为66.7%。作为副作用,1例患者出现轻微便秘,给予泻药治疗。16例患者中有1例发生光变应性皮疹。给予抗组胺药治疗后,他很快康复。

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