Legrand Mélanie, Delalande Flore, Blechet Claire, Kerdraon Rémy, Saint-Marc Olivier, Michenet Patrick
Service d'anatomie et cytologie pathologiques, hôpital de la Source, BP 86709, 45067 Orléans cedex 2, France.
Service d'anatomie et cytologie pathologiques, hôpital de la Source, BP 86709, 45067 Orléans cedex 2, France.
Ann Pathol. 2019 Aug;39(4):292-296. doi: 10.1016/j.annpat.2018.12.007. Epub 2019 Jan 31.
Microcystic variant of serous cystadenoma of the pancreas is a rare neoplasm; essentially located in the body or tail of the pancreas and associated with the von Hippel-Lindau. Often, patients are asymptomatic and the neoplasm is incidentally discovered. Usually radiographic manifestations are characteristic. Histopathological examination revealed uniform clear cuboidal cells; they can be confused with other clear cell neoplasms like renal cell carcinomas, well-differentiated neuroendocrine tumors and solid pseudopapillary tumors of the pancreas. Immunohistochemistry can be help to establish the diagnosis and to remove differential diagnosis. Serous cystadenoma is a benign neoplasm whose prognosis is excellent. We herein report two cases of microcystic serous cystadenomas of the pancreas diagnosed in two asymptomatic women and review analysis in the literature to remind the main features of this lesion and the main differential diagnosis.
胰腺浆液性囊腺瘤的微囊性变体是一种罕见的肿瘤；主要位于胰腺体部或尾部，与冯·希佩尔-林道病相关。患者通常无症状，肿瘤多为偶然发现。其影像学表现通常具有特征性。组织病理学检查显示细胞为均匀一致的透明立方状；可与其他透明细胞肿瘤混淆，如肾细胞癌、高分化神经内分泌肿瘤和胰腺实性假乳头状肿瘤。免疫组织化学有助于确诊并排除鉴别诊断。浆液性囊腺瘤是一种良性肿瘤，预后良好。我们在此报告两例在两名无症状女性中诊断出的胰腺微囊性浆液性囊腺瘤病例，并对文献进行回顾分析，以提示该病变的主要特征及主要鉴别诊断。
