埃及人群中27个X染色体短串联重复序列的基因多态性
Genetic polymorphism of 27 X-chromosomal short tandem repeats in an Egyptian population.
作者信息
Fukuta Mamiko, Gaballah Mohammed, Takada Kazushi, Miyazaki Hiroki, Kato Hideaki, Aoki Yasuhiro, Hamed Sameera Sh, ElMorsi Doaa A A, ElDakroory Sahar A
机构信息
Department of Forensic Medicine, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan.
Egyptian Forensic Medicine Authority, Ministry of Justice, Cairo, Egypt.
出版信息
Leg Med (Tokyo). 2019 Mar;37:64-66. doi: 10.1016/j.legalmed.2019.01.009. Epub 2019 Jan 24.
We presented allele frequencies of 27 X-chromosomal short tandem repeats (DXS6807, DXS9902, DXS6795, DXS6810, DXS10076, DXS10077, DXS10078, DXS10162, DXS10163, DXS10164, DXS7132, DXS981, DXS6800, DXS6803, DXS6809, DXS6789, DXS6799, DXS7424, DXS101, DXS7133, GATA172D05, DXS10103, HPRTB, GATA31E08, DXS8377, DXS10147, and DXS7423) obtained from 352 unrelated individuals in Egypt. No deviation from Hardy-Weinberg equilibrium was detected. Two pairs of adjacent loci showed significant linkage disequilibrium. In the principal component analysis plot, the Egyptian data were located between Europe and sub-Saharan Africa, away from Asia.
我们展示了从埃及352名无亲缘关系个体中获得的27个X染色体短串联重复序列（DXS6807、DXS9902、DXS6795、DXS6810、DXS10076、DXS10077、DXS10078、DXS10162、DXS10163、DXS10164、DXS7132、DXS981、DXS6800、DXS6803、DXS6809、DXS6789、DXS6799、DXS7424、DXS101、DXS7133、GATA172D05、DXS10103、HPRTB、GATA31E08、DXS8377、DXS10147和DXS7423）的等位基因频率。未检测到偏离哈迪 - 温伯格平衡的情况。两对相邻位点显示出显著的连锁不平衡。在主成分分析图中，埃及的数据位于欧洲和撒哈拉以南非洲之间，远离亚洲。
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