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科特迪瓦 X 染色体 STR 等位基因和单体型多样性。

Allele and haplotype diversity of X-chromosomal STRs in Ivory Coast.

机构信息

Department of Anatomy, Pharmacology and Legal Medicine, University of Turin, Corso Galileo Galilei 22, Turin, Italy.

出版信息

Int J Legal Med. 2011 Sep;125(5):749-52. doi: 10.1007/s00414-011-0591-4. Epub 2011 Jun 30.

Abstract

Twenty-one X-chromosomal short tandem repeat (STR) loci, including the six clusters of linked markers DXS10148-DXS10135-DXS8378 (Xp22), DXS7132-DXS10079-DXS10074 (Xq12), DXS6801-DXS6809-DXS6789 (Xq21), DXS7424-DXS101 (Xq22), DXS10103-HPRTB-DXS10101 (Xq26), DXS8377-DXS10146-DXS10134-DXS7423 (Xq28) and the loci DXS6800, GATA172D05 and DXS10011 were typed in a population sample from Ivory Coast (n=125; 51 men and 74 women). Allele and haplotype frequencies as well as linkage disequilibrium data for kinship calculations are provided. On the whole, no significant differences in the genetic variability of X-STR markers were observed between Ivorians and other sub-Saharan African populations belonging to the Niger-Kordofanian linguistic group.

摘要

21 个 X 染色体短串联重复(STR)位点,包括 6 个连锁标记簇 DXS10148-DXS10135-DXS8378(Xp22)、DXS7132-DXS10079-DXS10074(Xq12)、DXS6801-DXS6809-DXS6789(Xq21)、DXS7424-DXS101(Xq22)、DXS10103-HPRTB-DXS10101(Xq26)、DXS8377-DXS10146-DXS10134-DXS7423(Xq28)以及位点 DXS6800、GATA172D05 和 DXS10011,在来自象牙海岸的人群样本(n=125;51 名男性和 74 名女性)中进行了分型。提供了等位基因和单倍型频率以及用于亲属关系计算的连锁不平衡数据。总体而言,在 X-STR 标记的遗传变异性方面,象牙海岸人与属于尼日尔-科尔多凡语系的其他撒哈拉以南非洲人群没有显著差异。

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