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巴西针对晚期心力衰竭患者实施心脏移植项目。

Implementation of Heart Transplantation Program to Advanced Heart Failure Patients in Brazil.

作者信息

Marcondes-Braga Fabiana G, Bonatto Marcely Gimenes, Andrade Caio Ribeiro Alves, Bacal Fernando

机构信息

Heart Transplantation Department, Heart Institute (InCor), University of Sao Paulo, Sao Paulo, Brazil.

Heart Transplantation Department, Santa Casa de Misericórdia Hospital, Curitiba, PR, Brazil.

出版信息

Curr Heart Fail Rep. 2019 Feb;16(1):7-11. doi: 10.1007/s11897-019-0418-z.

DOI:10.1007/s11897-019-0418-z
PMID:30712146
Abstract

PURPOSE

Heart transplantation is the gold standard treatment for advanced heart failure. Left ventricular assist devices (LVADs), despite being a good option for these patients, are not quite available in developing countries. Time spent in heart transplant waiting list has increased lately even in regions where the number of transplants has also risen showing that a new strategy should be sought.

RECENT FINDINGS

Transplant process organization combined with multidisciplinary work are linked to better outcomes while improvement in donor's care and in pre-transplant evaluation might be opportunities to change the long waiting list scenario. For the first time in Brazil, a survey with the most expressive heart transplant centers has been made, which allows an overview of treatment of advanced heart failure in a developing country. We also described a model of heart transplant team, which has proved to be a success when compared to the largest heart transplant centers in Latin America.

摘要

目的

心脏移植是晚期心力衰竭的金标准治疗方法。尽管左心室辅助装置(LVADs)对这些患者来说是一个不错的选择,但在发展中国家却不太容易获得。即使在心脏移植数量有所增加的地区,在心脏移植等待名单上花费的时间最近也有所增加,这表明应该寻求一种新的策略。

最新发现

移植过程的组织与多学科合作与更好的结果相关联,而改善供体护理和移植前评估可能是改变长等待名单情况的机会。在巴西首次对最具代表性的心脏移植中心进行了一项调查,这使得我们能够对一个发展中国家晚期心力衰竭的治疗情况有一个全面的了解。我们还描述了一个心脏移植团队的模式,与拉丁美洲最大的心脏移植中心相比,该模式已被证明是成功的。

相似文献

1
Implementation of Heart Transplantation Program to Advanced Heart Failure Patients in Brazil.巴西针对晚期心力衰竭患者实施心脏移植项目。
Curr Heart Fail Rep. 2019 Feb;16(1):7-11. doi: 10.1007/s11897-019-0418-z.
2
Heart Transplant in Asia.亚洲的心脏移植
Heart Fail Clin. 2015 Oct;11(4):563-72. doi: 10.1016/j.hfc.2015.07.008.
3
Comparison of total artificial heart and biventricular assist device support as bridge-to-transplantation.作为移植桥梁的全人工心脏与双心室辅助装置支持的比较。
J Card Surg. 2016 Oct;31(10):648-653. doi: 10.1111/jocs.12823. Epub 2016 Aug 29.
4
Optimal Timing of Heart Transplant After HeartMate II Left Ventricular Assist Device Implantation.植入HeartMate II左心室辅助装置后心脏移植的最佳时机
Ann Thorac Surg. 2017 Nov;104(5):1569-1576. doi: 10.1016/j.athoracsur.2017.03.066. Epub 2017 Jun 24.
5
Severe right ventricular dysfunction is an independent predictor of pre- and post-transplant mortality among candidates for heart transplantation.严重右心室功能障碍是心脏移植候选者移植前和移植后死亡率的独立预测因素。
Arch Cardiovasc Dis. 2017 Mar;110(3):139-148. doi: 10.1016/j.acvd.2016.06.002. Epub 2017 Jan 20.
6
Impact of increased time at the highest urgency category on heart transplant outcomes for candidates with ventricular assist devices.增加处于最高紧急类别时间对心室辅助设备候选者心脏移植结局的影响。
J Heart Lung Transplant. 2016 Mar;35(3):326-334. doi: 10.1016/j.healun.2015.10.011. Epub 2015 Oct 8.
7
Sensitivity, ventricular assist devices, and the waiting game in heart transplantation: what's new?敏感性、心室辅助装置与心脏移植中的等待策略:有何新进展?
Crit Care Nurs Q. 2004 Jan-Mar;27(1):65-77. doi: 10.1097/00002727-200401000-00006.
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Donation After Cardiac Death: A Necessary Expansion for Heart Transplantation.心死亡后捐献:心脏移植的必要拓展。
Semin Thorac Cardiovasc Surg. 2019;31(4):721-725. doi: 10.1053/j.semtcvs.2019.05.010. Epub 2019 May 16.
9
Improved survival and decreasing incidence of adverse events with the HeartMate II left ventricular assist device as bridge-to-transplant therapy.使用HeartMate II左心室辅助装置作为桥接至移植治疗可提高生存率并降低不良事件发生率。
Ann Thorac Surg. 2008 Oct;86(4):1227-34; discussion 1234-5. doi: 10.1016/j.athoracsur.2008.06.030.
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Assessment of Heart Transplant Waitlist Time and Pre- and Post-transplant Failure: A Mixed Methods Approach.心脏移植等待名单时间及移植前后失败情况评估:一种混合方法研究
Epidemiology. 2016 Jul;27(4):469-76. doi: 10.1097/EDE.0000000000000472.

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Long-term Survival Following Heart Transplantation for Chagas Versus Non-Chagas Cardiomyopathy: A Single-center Experience in Northeastern Brazil Over 2 Decades.恰加斯病性心肌病与非恰加斯病性心肌病心脏移植后的长期生存:巴西东北部20多年的单中心经验
Transplant Direct. 2022 Jun 24;8(7):e1349. doi: 10.1097/TXD.0000000000001349. eCollection 2022 Jul.
2
Long-term mechanical assisted circulation devices.长期机械辅助循环装置
Sao Paulo Med J. 2022 May-Jun;140(3):329-330. doi: 10.1590/1516-3180.2022.140303122021.

本文引用的文献

1
OPTN/SRTR 2016 Annual Data Report: Heart.OPTN/SRTR 2016 年度数据报告:心脏。
Am J Transplant. 2018 Jan;18 Suppl 1:291-362. doi: 10.1111/ajt.14561.
2
The Registry of the International Society for Heart and Lung Transplantation: Thirty-fourth Adult Heart Transplantation Report-2017; Focus Theme: Allograft ischemic time.国际心肺移植学会登记处:2017年第34份成人心脏移植报告;重点主题:移植心脏缺血时间
J Heart Lung Transplant. 2017 Oct;36(10):1037-1046. doi: 10.1016/j.healun.2017.07.019. Epub 2017 Jul 20.