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对于心房颤动消融术,采用高功率(45-50 瓦)短时间治疗可降低并发症发生率。

Low complication rates using high power (45-50 W) for short duration for atrial fibrillation ablations.

机构信息

Silicon Valley Cardiology, PAMF and Sutter Health, East Palo Alto, California.

Texas Cardiac Arrhythmia Institute at St. David's Medical Center, Austin, Texas.

出版信息

Heart Rhythm. 2019 Feb;16(2):165-169. doi: 10.1016/j.hrthm.2018.11.031.

DOI:10.1016/j.hrthm.2018.11.031
PMID:30712645
Abstract

BACKGROUND

Many centers use radiofrequency (RF) energy at 25-35 W for 30-60 seconds. There is a safety concern about using higher power, especially on the posterior wall.

OBJECTIVE

The purpose of this study was to examine complication rates for atrial fibrillation (AF) ablations performed with high-power, short-duration RF energy.

METHODS

We examined the complication rates of 4 experienced centers performing AF ablations at RF powers from 45-50 W for 2-15 seconds per lesion. In total, 13,974 ablations were performed in 10,284 patients. On the posterior wall, 11,436 ablations used 45-50 W for 2-10 seconds, and 2538 ablations used power reduced to 35 W for 20 seconds. Esophageal temperature monitoring was used in 13,858 (99.2%).

RESULTS

Demographics were age 64 ± 11 years, male 68%, left atrial size 4.4 ± 0.7 cm, paroxysmal AF 37%, persistent AF 42%, longstanding AF 20%, antiarrhythmic drugs failed 1.4 ± 0.7, hypertension 54%, diabetes 15%, previous cerebrovascular accident/transient ischemic attack 7%, and CHADS-VASc score 2.1 ± 1.4. Procedural time was 116 ± 41 minutes. Complications were death in 2 (0.014%; 1 due to stroke and 1 due to atrioesophageal fistula), pericardial tamponade in 33 (0.24%; 26 tapped, 7 surgical), strokes <48 hours in 6 (0.043%), strokes 48 hours-30 days in 6 (0.043%), pulmonary vein stenosis requiring intervention in 2 (0.014%), phrenic nerve paralysis in 2 (0.014%; both resolved), steam pops 2 (0.014%) without complications, and catheter char 0 (0.00%). There was 1 atrioesophageal fistula in 11,436 ablations using power 45-50 W on the posterior wall and 3 in 2538 ablated with 35 W on the posterior wall (P = .021), although 2 of the 3 had no esophageal monitoring during a fluoroless procedure.

CONCLUSION

AF ablations can be performed at 45-50 W for short durations with very low complication rates. High-power, short-duration ablations have the potential to shorten procedural and total RF times and create more localized and durable lesions.

摘要

背景

许多中心使用 25-35 W 的射频 (RF) 能量进行 30-60 秒的治疗。使用更高的功率存在安全隐患,尤其是在后壁。

目的

本研究旨在探讨使用高功率、短时间 RF 能量进行心房颤动 (AF) 消融的并发症发生率。

方法

我们检查了 4 个经验丰富的中心的并发症发生率,这些中心在 RF 功率为 45-50 W 的情况下,对每个病变进行 2-15 秒的消融。总共对 10284 例患者进行了 13974 次消融。在后壁,11436 次消融使用 45-50 W 进行 2-10 秒,2538 次消融使用功率降低至 35 W 进行 20 秒。在 13858 次(99.2%)中使用了食管温度监测。

结果

人口统计学特征为年龄 64±11 岁,男性占 68%,左心房大小 4.4±0.7 cm,阵发性 AF 占 37%,持续性 AF 占 42%,长期 AF 占 20%,抗心律失常药物失败占 1.4±0.7,高血压占 54%,糖尿病占 15%,既往脑血管意外/短暂性脑缺血发作占 7%,CHADS-VASc 评分占 2.1±1.4。手术时间为 116±41 分钟。并发症包括 2 例死亡(0.014%;1 例因中风,1 例因食管-心房瘘),33 例心包填塞(2.4%;26 例经穿刺,7 例手术),6 例<48 小时的中风(0.043%),6 例 48 小时-30 天的中风(0.043%),2 例需要介入治疗的肺静脉狭窄(0.014%),2 例膈神经麻痹(0.014%;均已恢复),2 例蒸汽爆裂(0.014%)无并发症,导管炭化 0(0.00%)。在后壁使用 45-50 W 功率进行消融的 11436 次消融中有 1 例发生食管-心房瘘,而在后壁使用 35 W 功率进行消融的 2538 次中有 3 例(P=0.021),尽管其中 2 例在无氟过程中未进行食管监测。

结论

AF 消融术可以在 45-50 W 的短时间内以非常低的并发症发生率进行。高功率、短时间的消融有可能缩短手术和总 RF 时间,并产生更局部和持久的病变。

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